WPRIM Management System> DCMS> Acta Pharmaceutica Sinica> 2019> 54

Volume: 54

1. Evaluation of chemical consistency of triterpene acids in ethanol extracts of Poria and acetic ether extracts thereof by UPLC-QTOF-MS/MS with full scan and mimic MRM mode Page:130—137
2. Pepstatin Pr show anti-fibrosis effect related to YAP-TGFβ-Smad pathway Page:89—94
3. The anti-atherosclerotic effect and mechanism study of berberine in hyperlipidemic ApoE-/- mice Page:104—110
4. Delivery of miR-375 and doxorubicin hydrochloride by lipid bilayer coated hollow mesoporous silica nanoparticles for liver cancer therapy Page:151—158
5. Structure-activity relationship analysis of novel farnesyl transferase inhibitors Page:111—116
6. Improving the dissolution rate of water-insoluble diflunisal by γ-cyclodextrin metal-organic framework Page:29—35
7. In vitro-in vivo correlation of goserelin acetate microspheres Page:159—165
8. Effect of added halide ions and pH on the solubility of nebivolol hydrochloride and the evaluation of selected, discriminating dissolution media Page:54—60
9. Enhancement of water solubility and anti-tuberculosis activities by a novel artemisinin derivative Page:36—40
10. Complete chloroplast genome of Allium chinense: comparative genomic and phylogenetic analysis Page:173—181
11. Cyclosporin A osmotic pump tablets which can form supersaturated micelles Page:22—28
12. Improvement of in vitro dissolution and physical stability for spironolactone solid dispersion formulated with Soluplus Page:14—21
13. Two new compounds from rifamycin resistant mutant strain Streptomyces sp. HS-NF-1046R Page:117—121
14. An in vitro method for preliminarily screening competing agents to enhance drug permeation in cyclodextrin inclusion complexes Page:61—65
15. Effect of flufenamic acid on solubility, dissolution andpharmacokinetic behavior of sorafenib in MSNM@SFN Page:48—53
16. LC-MS analysis of sintilimab as an anti-PD-1 therapeutic mab for its improved hinge stability study Page:122—129
17. Phospholipidomics study of Jiegeng Decotion for LPS-induced acute lung injury in mice based on UHPLC-Q-Exactive Orbitrap/MS Page:144—150
18. Mechanisms of β-arrestin-biased GPCR signal transduction and advances in drug research Page:66—72
19. Detoxification mechanism of Jujubae Fructus and Crotonis Semen Pulveratum based on the toxicity of gastrointestinal system and diuretic effect in mice Page:95—103
20. The prediction of baicalin content in the extraction process of Scutellaria baicalensis by near-infrared spectroscopy combined with different variable selection methods Page:138—143
21. The identification of Sect. Cruciata (Gentiana) species using mtDNA nad1/b-c and nad5/d-e fragments Page:166—172
22. Research progress on pharmacodynamic substances of Chinese Medicine based on chromatographic techniques Page:73—81
23. Mechanism studies on solubility enhancement of ibuprofen by complexation with nicotinamide Page:41—47
24. Application of methods on target identification and validation of label-free natural products Page:82—88
25. Improving oral absorption of BCS Ⅱ drugs by increasing solubility: frequently overlooked permeability Page:1—7
26. Solubilization and protection of curcumin by mixed surfactants Page:8—13
27. Relative molecular weight determination of astragalus polysaccharides for injection Page:348—353
28. Feasibility exploration of discriminating red yeast rice for different applications by secondary metabolite fingerprints Page:354—359
29. Antitumor status analysis on the co-delivery systems regarding the active ingredients of Chinese herbs combined with chemotherapeutic drugs Page:258—268
30. Rg1 alleviates the cholestatic liver fibrosis throughregulation of NF-κB/VCAM-1 Page:321—328
31. Genistein regulates miR-21 to promote the apoptosis in LPS-activated RAW264.7 cells Page:281—287
32. Beneficial effects of nanosuspensions of honokiol in mice on high fat diet through suppression of hepatic gluconeogenesis Page:288—293
33. Applications of ionic liquids in drug research Page:245—257
34. Rapid and simultaneous determination of nifedipine and dehydronifedipine in human plasma Page:360—365
35. A smart near-infrared spectroscopy evaluation system for quality management of Chinese medicinal materials based on quality markers Page:197—203
36. Research advancement in the construction and applications of microfluidic devices for in vitro blood-brain barrier research Page:269—280
37. Discovery of quality markers of traditional Chinese medicine compounds and visualization technology of content-effect colour atla Page:222—227
38. Research progress of circular RNA in regulating vascular endothelial dysfunction Page:228—234
39. Protective effects of scutellarin on diabetic cardiomyopathy in mice Page:294—300
40. Differential mechanism of toxicity in normal and blood-stasis mice following Rhizoma Curcumae exposure based on "YOU-GU-WU-YUN" theory Page:329—334
41. A hypothesis on the Q-markers based on characteristics of opposite-effect of herbs: an example of Sanqi Page:211—221
42. Design, synthesis and anticancer activity studies of oleanolic acidderivatives targeting mTOR Page:335—342
43. Comparison of antithrombotic effects between salvianolic acid A and aspirin Page:301—307
44. The concept, core theory and research methods of Chinesemedicine quality markers Page:187—196
45. Research strategy for quality-biomarkers of traditional Chinese medicine based on effect benchmarks Page:204—210
46. Diversity and isolation parameters of endophytes from Glycyrrhiza uralensis of different habitats Page:373—379
47. Design and expression of FGF23 inhibitor in Pichia pastoris Page:380—385
48. Anti-inflammatory activity of two new sesquiterpenoids from Radix Angelicae Pubescentis Page:343—347
49. Evaluation of the estrogenic effects of rehmapicrogenin Page:308—312
50. Pharmacological network-based study on interventional mechanism of Gu-Chang-Zhi-Xie pills for treatment of irritable bowel syndrome Page:482—493
51. Mechanism and application of acid-sensitive peptides in drug delivery Page:440—447
52. The determination of diflucortolone in rabbit plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS) Page:522—527
53. Metabolism and pharmacokinetics of covalent tyrosine kinase inhibitors Page:432—439
54. Predictive performance and analysis of a vancomycin population pharmacokinetic model in Chinese pediatric patients Page:528—532
55. Preparation of disulfiram naonosuspensions and their anti-tumor efficacy in vitro and in vivo Page:565—573
56. Progress in the study of the association between the lipid droplets and hepatitis C virus life cycle Page:393—398
57. Recent progress in the research on pyrrolizidine alkaloids from Chinese medicinal herb "Zicao" and their metabolic toxicity Page:420—431
58. The "target + activity" method for rapid discovery of active compounds targeting Hsp90 in pancreatic cancer cells from Physalis angulata L. Page:475—481
59. Screening and validation of antithrombotic effective components group from Trichosanthes extract Page:502—509
60. Mechanisms of ferroptosis and its involvement in Parkinson's disease Page:399—406
61. Mechanism of melanoma growth inhibition by exogenous mitochondria Page:463—468
62. A new strategy to intervene tumor metabolism: regulatory targets for amino acid metabolism and advances in drug research Page:407—419
63. Cloning and enzymatic function characterization of a novel tropinone reductase I (DaTRI 2) in Datura arborea Page:574—581
64. Liposomal melatonin dry powder inhalers for the treatment of primary lung cancer Page:555—564
65. Anti-osteosarcoma activity and underlying molecular mechanism of a novel small molecule spermine oxidase inhibitor SI-4650 Page:454—462
66. The role of pinocembrin in t-PA thrombolysis-induced hemorrhagic transformation Page:448—453
67. Effect of zwitterionic polymer chain length on mucus penetration and cellular uptake of nanoparticles Page:547—554
68. Synthesis and anti-angiogenic activity of a novel microtubule inhibitor IMB5046 Page:469—474
69. A simple strategy for delivery of carbon monoxide against septic lung injury Page:540—546
70. Design, synthesis and of antitumor activity study of coumarinderivatives bearing benzothiazole or benzene moiety Page:514—521
71. Comparative study on the effects of different proportions of ginkgo ketoester and donepezil on anti-dementia based on principal component analysis and multi-attribute comprehensive index methods Page:660—669
72. Quantification of norfloxacin in human plasma by LC-MS/MS and validation of the analytical method Page:695—700
73. Strategies for enhancing nanoscale brain targeting drug delivery Page:629—637
74. Experimental study on the effect of Sishen Wan on intestinal flora in rats with diarrhea-type irritable bowel syndrome Page:670—677
75. Screening for potential bioactive components of Yin-zhi-huang using high bilirubin HepaRG cells incubating with serum from animals Page:645—652
76. Establishment of a screening model for compounds uncoupling the interaction of nNOS with PSD-95 Page:638—644
77. The effects of Huangqin Tang on oxidative stress and ulcerative colitis in rats through the Nrf2 signal pathway Page:653—659
78. Influence of ceftriaxone on pharmacokinetics, anticoagulation andantithrombotic effects of phenolic acids from Danhong injection in rats Page:701—709
79. Lorlatinib: a third generation ALK inhibitor for treatment of non-small cell lung carcinoma Page:601—610
80. Advances in understanding exosomes-mediated tumor chemoresistance Page:594—600
81. Idiosyncratic hepatotoxicity evaluation of Cortex Dictamni based on immune stress Page:678—686
82. Relationship between Rho GTPase family regulation and vascular endothelial barrier function Page:587—593
83. Qualitative and quantitative analysis of palbociclib Page:710—713
84. A new lignan from the hawk tea Page:692—694
85. Pharmacokinetic characteristics of 14CCHMFL-FLT3-122 in rats Page:714—719
86. Pharmaceutical mechanism and control strategy for storage of ellagic acid stably in traditional Chinese medicine oral liquid Page:737—745
87. Hypoxia inducing factor related genetic adaptation in high-altitude and pharmacological modulation Page:611—619
88. In vitro study of black phosphorus quantum dot-loaded liposomes for photothermal therapy of cervical cancer Page:729—736
89. Synthesis and antitumor activity of fluoroquinolone C-3 arylidene thiazolone derivatives from ciprofloxacin Page:687—691
90. The progress in the development of HIV inhibitors targeting protein-protein interactions Page:620—628
91. Identification of Ophiocordyceps sinensis and its adulterants based on portable and CFX96 real-time fluorescent PCR systems Page:746—752
92. Investigation on the inflammation network mechanisms of Wutou decoction acting on neuropathic pain Page:1054—1061
93. Phosphoglycerate kinase 1 and cancer Page:978—983
94. Medications regulate autophagy for treatment of Alzheimer's disease Page:984—990
95. Advances in research on exosomes as drug delivery vehicles Page:1010—1016
96. Preparation and quality evaluation of levocarnitine thermosensitive in situ gel Page:1115—1122
97. Effect on tumor growth inhibition activity of Gekkoswinhonis Guenther with different extent of broiling on H22 tumor-bearing mice Page:1048—1053
98. Quality analysis of different grades of Glycyrrhiza Polygalae Radix slices Page:1082—1087
99. Pharmacokinetics of two types of dipropofol crystal tablets in Beagle dogs Page:1088—1091
100. Smart fluorescent nano-delivery system for breast cancer cell tracing and growth inhibition Page:1123—1131
101. Experimental study of bicyclol for type 2 diabetic treatment using KKAy mice Page:1041—1047
102. Examination of the correlation between grades, chemicalcharacteristics and anti-fatigue effect of Astragali Radix Page:1092—1100
103. Effects of Jiawei Foshou San capsule on rat hepatic cytochrome P450 enzymes invitro and invivo Page:1101—1107
104. The characteristics and functions of CtXTH1: the gene booststhe corolla elongation in safflower Page:1132—1140
105. Advances in JAK2 inhibitors for treatment of myeloproliferative neoplasms Page:971—977
106. Research progress of drug delivery system with "gatekeeper" Page:1017—1025
107. 2018 DMPK research progress in China Page:963—970
108. Research progress on the inhibitors against factor XI Page:991—999
109. Therapeutic effects of artificial musk on acute ischemic stroke and subarachnoid hemorrhage in rats Page:1036—1040
110. Design, synthesis and biological evaluation of inhibitors of urate transporter 1 (URAT1) Page:1069—1074
111. Alkaloids from an aqueous extract of Uncaria rhynchophylla Page:1075—1081
112. Metabolism of a promising anti-tumor agent CAT3 in vitro Page:1108—1114
113. Dynamic changes of cyclophosphamide-induced liver injury in mice Page:1062—1068
114. TRIM25 enhances EGFR stability and signaling activity to promote lung cancer progression Page:1026—1035
115. Regulatory effect of mulberry leaf components on intestinal microflora in db/db mice Page:867—876
116. The mechanism study of protecting kidney of Erzhi Pill based on network pharmacology Page:877—885
117. Hypothesis on "one output multi-source" of traditional Chinese medicine complex system Page:801—807
118. Mechanisms of doxorubicin resistance of breast cancer MCF-7 cells mediated by exosomes Page:861—866
119. Progress in metabolomics research of diabetes Page:828—837
120. Application of Mycobacterium marinum infected zebrafish for evaluation of anti-tuberculosis drugs Page:854—860
121. Therapeutic perspectives of intestinal probiotics A. muciniphila in metabolic disorders Page:768—777
122. Recent advances in enzyme inhibitor screening based on mass spectrometry Page:818—827
123. Isolation of a novel disintegrin containing Arg-Gly-Asp tripeptide sequence from Gloydius brevicaudus venom and investigation of its biological activities Page:897—905
124. Exploration of non-clinical pharmacodynamics evaluation system of amyotrophic lateral sclerosis Page:788—800
125. Synthesis and evaluation of a dendritic poly(L-glutamic acid)-graft-polyethylenimine copolymer as an efficient gene delivery vector Page:919—926
126. Comparison and theoretical modeling of capillary electrophoresis analysis for the interaction between caffeine and serum proteins Page:906—912
127. Effects and mechanism of 3,5,6,7,4'-pentamethoxyflavone forblocking arenavirus entry Page:838—845
128. Accumulation of nitidine chloride in rat heart and the underlying mechanism Page:913—918
129. Identification of Chinese medicinal materials Stellariae Radix and its adulterants using DNA barcoding Page:937—943
130. Advances and applications of lysine acetylation Page:778—787
131. Biodegradable micelles for two-photon photodynamic therapy in a mouse model of breast cancer Page:927—936
132. The hypolipidemic and anti-atherosclerotic effects of acacetin and its mechanism of action in mice Page:846—853
133. Synthesis, in vitro evaluation and in vivo imaging of a highly selective hydrazine bioluminescent probe based on luciferin-luciferase system Page:886—891
134. Analysis of transcriptomes to explore genes contributing to iridoid biosynthesis in Gentiana waltonii and Gentiana robusta (Gentianaceae) Page:944—953
135. Secondary metabolites from Corynespora cassiicola J9, an endophytic fungus associated with Blumea balsamifera (L.) DC. Page:892—896
136. Deep learning in drug design and discovery Page:761—767
137. Predicting and validating the mechanism of Trichosanthes mediated anti-myocardial ischemia-reperfusion injury by network pharmacology Page:1234—1240
138. Progress in characteristics and application of olfactory bulbectomy animal model Page:1157—1165
139. Caffeoyl quinic acids in Chrysanthemum morifolium improve LPS-induced HUVEC vascular endothelial cell injury by regulating ERK/MAPK signaling pathway Page:1207—1213
140. Recent advances in microglial activation for treatment of chronic neuropathic pain Page:1166—1173
141. Down-regulation of miR-205-5p sensitizes HNE1/DDP to cisplatin induced apoptosis in vitro Page:1200—1206
142. Assessment of monoclonality of cell bank for recombinant biologics production Page:1325—1329
143. Progress in research of the structure and function of Elabela/APJ signal Page:1174—1178
144. Comparison of intestinal bacteria and inflammatory cytokine expression in rats with ulcerative colitis after treatment of three regiments Page:1241—1250
145. Simultaneous determination of three chemical compounds in embryonic parenchyma cells and endocarp stone cells of Arctii Fructus at five different growth stages by UFLC-MS/MS Page:1265—1270
146. Comparative analysis of aconitine alkaloids in aconite tube using direct ionization and wooden tip spray mass spectrometry Page:1271—1276
147. Research progress, chemistry, manufacturing and controlsconsiderations of mesenchymal stem cell products Page:1317—1324
148. Cloning and sequence analysis of codeine-O-demethylase gene from Papaver somniferum and Papaver rhoeas Page:1312—1316
149. Repositioning drug discovery for Alzheimer's disease based on global marketed drug data Page:1214—1224
150. Observation on efficacy, pharmacokinetic behaviors and safety of new modified RNA oligonucleotide targeting Foxo-1 via two routes of administration Page:1251—1256
151. Tryptanthrin derivative CY-1-4 nanoparticle induces ferroptosis in B16-F10 cells Page:1288—1296
152. Anti-diabetic effects of the fraction of alkaloids from Ramulus Mori, an innovative Sangzhi alkaloids as an α-glucosidase inhibitor Page:1225—1233
153. Analytical capabilities of matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) and its potential applications in medicinal plants Page:1179—1189
154. A new cadalene sesquiterpene glycoside from Dendrobium nobile Page:1257—1259
155. A new oleanane type triterpenoid from Viburnum taitoense Hayata Page:1260—1264
156. The black phosphorus quantum dots-based photothermal effect on dendritic cells activation Page:1297—1302
157. First-in-class small molecule drugs in 2018 Page:1145—1156
158. Advances in the molecular mechanism of salvianolic acid and tanshinone for intervention of diabetic kidney disease Page:1356—1363
159. Metabolomic screening for diagnostic biomarkers of drug-induced chronic liver injury related cirrhosis Page:1449—1456
160. Network pharmacology-based study on mechanisms of antipyretic action of Pueraria radix Page:1409—1416
161. Mechanisms of inhibition of invasion and metastasis of nasopharyngeal carcinoma cells by neferine through its influence on microRNAs Page:1417—1423
162. Anti-tumor activity and mechanisms of isorhamnetin in combination with sorafenib for renal cancer Page:1424—1430
163. Ampelopsin inhibited apoptosis and migration of SMMC-7721 cells through MAPKs signaling pathway Page:1431—1438
164. Advances in the mechanisms of acquired resistance to EGFR-tyrosine kinase inhibitors in non-small cell lung cancer Page:1364—1371
165. The roles of sphingosine-1-phosphate and its receptor in Mycobacterium tuberculosis infection and novel antibiotics discovery Page:1348—1355
166. A new disubstituted succinate from the roots of Tagetes erecta Page:1457—1460
167. Energy metabolism disorder and diseases: from effects to potential targets Page:1372—1381
168. Metabolomic investigate into the serum of pulmonary hypertension Beagle dogs and the effect of sGC003 Page:1470—1475
169. Cloning and characterization of UDP-L-rhamnose synthase 1/2 from Fallopia multiflora Page:1515—1523
170. Exploring the molecular mechanism of aqueous extract from Huang qi on doxorubicin induced nephropathy in rats using transcriptome sequencing technique Page:1439—1448
171. Construction and preliminary study of multifunctional drug delivery system based on hollow mesoporous copper sulfide nanoparticles Page:1502—1508
172. Research progress about the anti-aging effect and mechanism of flavonoids from traditional Chinese medicine Page:1382—1391
173. Advances in chemical synthesis of dual inhibitors of HIV integrase and ribonuclease H Page:1392—1401
174. Studies on the metabolism of a triptolide derivative (5R)-5-hydroxytriptolide in vitro Page:1484—1492
175. Synthesis and neuroprotective activity of resveratrol-3-n-butylphthalide hybrids Page:1461—1469
176. Preparation and characterization of drug-loaded polymer-lipid hybrid nanoparticles with tunable surface hydrophobicity Page:1509—1514
177. The anti-ZIKA virus activity of tenofovir disoproxil fumarate in vitro Page:1582—1587
178. Progress in the study of association between cellular senescence and organ fibrosis Page:1531—1537
179. The molecular mechanism of stroke treatment by Fufang Longmai Ningfang based on network pharmacology Page:1588—1596
180. Ginsenoside CK induces apoptosis of human liver cancer SMMC-7721 cells through inhibition of TGF-β1/Smads signaling pathway Page:1606—1611
181. Research progresses of small molecule inhibitors targeting TGF-β and its receptors Page:1538—1546
182. Lipidomics study on intervention by Uncaria on hepatic metabolic disorder in spontaneously hypertensive rats Page:1636—1644
183. Identification of chemical constituents in Aster tataricus by UHPLC-Q-TOF-MS Page:1645—1654
184. Progress in research of Trp-IDO1,2/TDO2-Kyn metabolic pathway in the pathogenesis of rheumatoid arthritis Page:1547—1553
185. Identification of impurity profile in tinidazole glucose injection by UPLC-MS Page:1655—1660
186. Simultaneous quantitative analyses of eight components in Artemisia capillaris Thunb standard decoction based on a quantitative method of multi-components with a single-marker Page:1661—1666
187. Preliminary study on the mechanism of anaphylactoid reaction induced by natural product germacrone Page:1667—1672
188. Study on chemical constituents of flavonoids in Turpinia arguta Page:1620—1626
189. Quality ecotype of Panax quinquefolium L. based on heredity-chemistry-ecology characteristics Page:1695—1705
190. Modern research approaches and strategies for compatibility effects and efficacy components of herbal pairs Page:1564—1573
191. Establishment of a new genus of filovirus (Mengla virus) entry evaluating system and entry inhibitors discovery Page:1612—1619
192. Effect of carrier size and surface morphology on the aerosolization of formulation in a capsule-based dry powder inhaler Page:1673—1679
193. Recent advances in study of drugs against Gram-negative pathogens Page:1554—1563
194. Research progress of ferritin nanocage for drug delivery systems Page:1574—1581
195. Anti-MRSA activities of cycloberberine derivatives with a novel chemical scaffold Page:1627—1635
196. Intranasal tetrandrine temperature-sensitive gel for treatment of post-traumatic stress disorder Page:1680—1687
197. Anti-metastatic effect of diallyl trisulfide-exosome in mouse melanoma Page:1688—1694
198. Application prospect of organoids and 3D-cell models in evaluation of cardiotoxicity of traditional Chinese medicine Page:1888—1894
199. The action and mechanism of ethanol extract of Cichorium glandulosum on type 2 diabetes mellitus accompanied with nonalcoholic fatty liver disease based on systems pharmacology Page:2019—2030
200. Isorhamnetin activates Sirt1/PGC-1α signaling pathway to inhibit MPP+-induced SH-SY5Y cell injury Page:1976—1981
201. Comparative study on the effect of Danggui-Chuanxiong herb pair on vasoactive substances and adhesion molecules in the serum of acute blood stasis in rats using PLS-DA and multi-attribute comprehensive index methods Page:1909—1917
202. Sequence analysis of therapeutic monoclonal antibody Page:2113—2117
203. Sophoral flavones inhibit proliferation of cardiac fibroblasts via regulating the expression of prohibitin Page:1903—1908
204. Cardiac safety evaluation of berberine combining with berberine-derived medicine Page:1895—1902
205. Exploring molecular mechanisms of anti-platelet adhesion of Chinese medicine for promoting blood circulation and removing blood stasis by activity screen and network analysis Page:1990—1999
206. Advances in research on mass spectrometry based chiral amino acid analysis for quality control of racemic peptide impurities Page:1958—1964
207. Effects of borneol on the pharmacokinetics of vinpocetine in rats Page:2064—2068
208. Mechanisms of eleutheroside for treatment of diabetes mellitus type 2 based on network pharmacology Page:1982—1989
209. Preparation and characterization of rivaroxaban as an anticoagulant Page:2069—2073
210. Advances in research on the mechanism of long-QT syndrome caused by traditional Chinese medicine affecting hERG potassium channel Page:1881—1887
211. Comparative study for morphological identification, chemical component analysis, and DNA barcode determination of three plants and their varieties in Genus Mentha Page:2083—2088
212. Fingerprint analysis and multi-component determination of Leonurus japonicus by high performance liquid chromatography Page:2059—2063
213. An exploration into the therapeutic effects and molecular mechanisms of paeoniflorin in the treatment of adjuvant-induced arthritis rats by a network pharmacology-based research strategy Page:2000—2010
214. Calculating freezing point of NaH2PO4-K2HPO4 mixed electrolyte solution with semi-empirical hydration model Page:2089—2092
215. Pharmacological network-based study on quality control of Carthamus tinctorius L. for safflower injection Page:2074—2082
216. Anti-cancer activity of two new triterpenes from Brassica rapa Page:2049—2054
217. Recent advances in LncRNAs and chronic kidney disease Page:1918—1925
218. Recent advances of PIM kinase and its small-molecule inhibitors Page:1926—1939
219. The discussion on a proposed quality similarity assessment criteria of rituximab biosimilar Page:2118—2125
220. Design, synthesis, and biological evaluation of novel polymyxin B analogues Page:2031—2038
221. Sijunzi Tang improves the efficacy of gefitinib through pre-metastatic niche Page:2011—2018
222. Study on the surface fungus diversity of commercially Platycladi semen based on high-throughput sequencing technology Page:2100—2105
223. In vivo fate study of drug nanocarriers: the applications of environment-responsive fluorescent dyes Page:1965—1975
224. Chemistry, manufacturing and controls regulatory considerations for marketing authorization application of therapeutic antibody in China Page:2126—2134
225. Analysis of chloroplast genome and its characteristics of medicinal plant Sophora flavescens Page:2106—2112
226. Application of benzoxaboroles compounds in medicinal chemistry Page:1940—1948
227. Flavonoids from the aerial parts of Lespedeza cuneata Page:2055—2058
228. Bioadhesive pellets of astragalosides: preparation and adhesive evaluation based on the physical properties of wet mass Page:2093—2099
229. Research on antitumor active components and mechanisms of natural products Page:1949—1957
230. Design, synthesis and inhibitory activity of indoleamine 2,3-dioxygenase 1 inhibitors Page:2039—2048
231. The roles of m6A in cancer biology and its targeted therapy Page:1771—1782
232. Mechanisms of metabolite-triggered oncogenic signaling in cancer Page:1755—1770
233. Advances of microenvironment-activated nanosized drug delivery system for cancer immunotherapy Page:1802—1809
234. Advanced research and technology development of antibody-drug conjugates Page:1810—1817
235. Advances in hyperprogressive disease of PD-1/PD-L1 antibody drugs and rational drug therapy Page:1735—1740
236. Non-coding RNA and tumor immune regulation Page:1783—1791
237. Research progress in immunotherapy for glioblastoma Page:1792—1801
238. The mechanism and research progress of drug resistance of PD-1/PD-L1 immunotherapy in tumors Page:1728—1734
239. Research progress of tumor immune and tumor metabolic drug targets Page:1718—1727
240. Review on clinical research progress of immunotherapy in liver cancer Page:1749—1754
241. Construction and anti-tumor efficacy of a peptide vaccine that targets calcium-binding protein S100A9 Page:1837—1844
242. Mechanistic advancement in chemotherapeutic agents modulated antitumor immune response Page:1741—1748
243. Research progress of dendritic cells anti-tumor vaccine stimulated by mRNA Page:1818—1823
244. The antitumor activity of STAT3 target inhibitor Bt354 andmolecular mechanism of anti-prostate cancer Page:1851—1857
245. The effects of different stimulators on the activation of human lymphocytes Page:1863—1867
246. Research advancement of succinyl-CoA transferase SCOT in tumor metabolism Page:1831—1836
247. DEPTOR improves cisplatin chemosensitivity in esophageal squamous cell carcinoma cells by inducing Caspase-1-mediated pyroptosis Page:1845—1850
248. Research progress of carnitine palmitoyltransferase 1in tumor immunotherapy Page:1824—1830
249. Post-translational modifications of proteins and cancer immunotherapy Page:1711—1717
250. Establishment and optimization of an enzyme-cell based high-throughput screening platform for IDO1 inhibitors Page:1868—1874
251. The optimization and application of cell-based screening model for IL-17-mediated signaling pathway Page:1858—1862
252. Establishment and application of STING agonist in-vitro screening model Page:1875—1880
253. Measurement of antiplatelet aggregation and potency of hirudo Page:2178—2183
254. Experimental study of photodynamic therapy using a new photosensitizer BF01 for human liver cancer Page:2251—2255
255. Research progress on anti-depression effects of ginsenosides Page:2204—2208
256. Determining the effect of Huangqi on the pharmacokinetics of six different alkaloids from Fuzi in rats by LC-MS Page:2289—2295
257. The protective effect of Qizhi hypoglycemic tablet on foot ulcer in streptozotocin-induced diabetes in rats Page:2256—2266
258. Effect and mechanism of Huangkui capsuleon reduction of uremic toxin accumulation in an animal model of chronic kidney disease Page:2267—2276
259. Progress in research of switchable chimeric antigen receptor T cells Page:2209—2213
260. Quality control of Shuanghuanglian preparations using an effect-constituent index Page:2149—2154
261. Current situation and the trend in impurity profiling of chemical drugs Page:2214—2231
262. Qualitative and quantitative analysis of cyclovirobuxine D and related substances by HPLC-CAD in the active pharmaceutical ingredient of Huangyangning tablets Page:2303—2307
263. Quality evaluation and toxicity assay for injectable traditional Chinese medicine using Microtox technology Page:2189—2194
264. Molecular identification and genetic relationship of Fritillaria cirrhosa and related species based on DNA barcode Page:2326—2334
265. UHPLC quantification and brain permeability study of sinomenine and ligustrazine in CQM after single intravenous administration Page:2308—2315
266. Diversity of microbiota composition of traditional Chinese medicine of Faeces Trogopterori from Shangluo, Shanxi province by sequence of the bacterial 16S rRNA gene Page:2335—2339
267. Research progress of Pickering emulsion drug delivery systems Page:2232—2239
268. Bioassay method for Compound Danshen Tablets based on a platelet aggregation inhibition test Page:2184—2188
269. A new sesquiterpene glycoside from Osmanthus fragrans var. aurantiacus Page:2277—2281
270. A new furocoumarin from the stems of Clausenalansium Page:2282—2285
271. Plasma proteins regulating in vivo performance of liposomes Page:2240—2250
272. A new 2,3-dioxoflavonoid from the aerial part of Hypericum perforatum Page:2286—2288
273. Preparation of lipid membrane-wrapped nanoparticles loaded with metformin polymer and doxorubicin and evaluation of their therapeutic effect on breast cancer Page:2316—2325
274. Bioassay of ansamitocin by Trichoderma plate Page:2340—2344
275. Establishment of an antibacterially effective components fingerprint for quality evaluation of Scutellariae Radix (Huangqin) Page:2155—2161
276. Quality evaluation of different processed products of Aconiti Lateralis Radix Praeparata combining bioassay and toxicity detection Page:2169—2177
277. Construction and application of effect-related near-infrared spectroscopy for traditional Chinese medicines — Exemplification by rhubarb dispensing granules Page:2162—2168
278. Comparative study on the suitability of chemical fingerprint and anti-platelet aggregation/anti-inflammatory biopotency in the overall quality evaluation of Xiaojin pills Page:2195—2203
279. Application of an effect-constituents index for the quality evaluation of the traditional Chinese medicine rhubarb Page:2141—2148
280. Research progress of traditional Chinese antidepressant herb-pair Page:235—244
281. Preparation and <italic>in vitro</italic> evaluation of phospholipid-coated silver-graphene quantum dot multifunctional nanoparticles Page:366—372