WPRIM Management System> DCMS> Acta Pharmaceutica Sinica> 2012> 47> 3

Volume: 47 Issue: 3

1. Differential proteins in esophageal squamous cell line EC9706/CDDP identified by SILAC quantitative proteomic approach. Page:409—416
2. NNIspm, a polyamine derivative, induces cellular senescence of human hepatoma HepG2 cells and its molecular mechanism. Page:405—408
3. Cu2+ and Zn2+-induced aggregation of amyloid-beta peptide. Page:399—404
4. Preparation and characterization of mono PEGylated recombinant human interferon omega. Page:393—398
5. Binding mechanism of traditional Chinese medicine active component 5-hydroxymethyl-furfural and HSA or BSA. Page:385—392
6. Synthesis of diethylenetriamine polydentate ligands and their DNA-cleaving activity. Page:380—384
7. ESI fragmentation studies of six unusual nucleotide sugars. Page:374—379
8. Design, synthesis and evaluation of malonic acid-based PTP1B inhibitors. Page:367—373
9. Sesquiterpenes and an intermediate 1alpha, 6beta, 11-eudesmanetriol in the biosynthesis of geosmin from Streptomyces sp. Page:364—366
10. Multi-substituted N-phenyl-2, 2-dichloroacetamide analogues as anti-cancer drugs: design, synthesis and biological evaluation. Page:354—363
11. Research progress of the relationship between microglia and cerebral ischemia. Page:346—353
12. Advances in the study of synergistic effect of anti-biofilm agents. Page:339—345
13. Research progress of layer-by-layer self-assembly technique in drug delivery. Page:332—338
14. Current applications of high-throughput DNA sequencing technology in antibody drug research. Page:322—331
15. Design of acetylcholinesterase inhibitor for Alzheimer's disease therapy: from multi-binding site inhibitors to multi-target directed ligands. Page:313—321
16. Activity of cyclic diguanylate (c-di-GMP) in bacteria and the study of its derivatives. Page:307—312
17. The application of small molecule bioactive probes in the identification of cellular targets. Page:299—306
18. Research progress of graphene-based materials in the application to biomedicine. Page:291—298
19. Chemical approaches for trapping protein thiols and their oxidative modification. Page:280—290
20. Progress in the study of some important natural bioactive cyclopeptides. Page:271—279
21. Recent advance in carbohydrate-based cancer vaccines. Page:261—270
22. Recent advance in carbohydrate-based cancer vaccines. Page:261—70
23. Progress in the study of some important natural bioactive cyclopeptides. Page:271—9
24. Chemical approaches for trapping protein thiols and their oxidative modification. Page:280—90
25. Research progress of graphene-based materials in the application to biomedicine. Page:291—8
26. The application of small molecule bioactive probes in the identification of cellular targets. Page:299—306
27. Activity of cyclic diguanylate (c-di-GMP) in bacteria and the study of its derivatives. Page:307—12
28. Design of acetylcholinesterase inhibitor for Alzheimer's disease therapy: from multi-binding site inhibitors to multi-target directed ligands. Page:313—21
29. Current applications of high-throughput DNA sequencing technology in antibody drug research. Page:322—31
30. Research progress of layer-by-layer self-assembly technique in drug delivery. Page:332—8
31. Advances in the study of synergistic effect of anti-biofilm agents. Page:339—45
32. Research progress of the relationship between microglia and cerebral ischemia. Page:346—53
33. Multi-substituted N-phenyl-2, 2-dichloroacetamide analogues as anti-cancer drugs: design, synthesis and biological evaluation. Page:354—63
34. Sesquiterpenes and an intermediate 1alpha, 6beta, 11-eudesmanetriol in the biosynthesis of geosmin from Streptomyces sp. Page:364—6
35. Design, synthesis and evaluation of malonic acid-based PTP1B inhibitors. Page:367—73
36. ESI fragmentation studies of six unusual nucleotide sugars. Page:374—9
37. Synthesis of diethylenetriamine polydentate ligands and their DNA-cleaving activity. Page:380—4
38. Binding mechanism of traditional Chinese medicine active component 5-hydroxymethyl-furfural and HSA or BSA. Page:385—92
39. Preparation and characterization of mono PEGylated recombinant human interferon omega. Page:393—8
40. Cu2+ and Zn2+-induced aggregation of amyloid-beta peptide. Page:399—404
41. NNIspm, a polyamine derivative, induces cellular senescence of human hepatoma HepG2 cells and its molecular mechanism. Page:405—8
42. Differential proteins in esophageal squamous cell line EC9706/CDDP identified by SILAC quantitative proteomic approach. Page:409—16