WPRIM Management System> DCMS> Acta Pharmaceutica Sinica> 2003> 38

Volume: 38

1. Effect of surfactants on the in vitro and in vivo properties of amphotericin B liposome. Page:471—474
2. Enhancement of gastrointestinal absorption of chitosan-coated insulin-loaded poly (lactic-co-glycolic acid) nanoparticles. Page:467—470
3. Preparation of albendazole polybutycyanocrylate nanoparticles and study on its pharmaceutical properties and tissue distribution. Page:462—466
4. Pharmacokinetics of the alkaloids from the processed seeds of Strychnos nux-vomica in rats. Page:458—461
5. Determination of finasteride in human plasma by HPLC-MS. Page:455—457
6. Study on the combination principles about aconite roots by electrospray ionization mass spectrometry. Page:451—454
7. Pharmacokinetic study on spinosin in rat plasma after oral administration of suanzaoren extract at a single dose. Page:448—450
8. Studies on the chemical constituents of Cirsium japonicum DC. Page:442—447
9. Studies on physico-chemical properties and hypoglycemic activity of complex polysaccharide AMP-B from Atractylodes macrocephala Koidz. Page:438—441
10. Study on the active spirostanol saponins of Gualou xiebai baijiutang. Page:433—437
11. A new alkaloids isolated from tetraploidy banlangen. Page:430—432
12. Synthesis and drug resistant reversal activities of taxane-like multi-drug resistant reversal agents. Page:424—429
13. Effect of lipopolysaccharide on expression of interleukin-6 in human synoviocyte from patients with rheumatoid arthritis. Page:420—423
14. Effect of adenosine A1 receptor antagonist on learning and memory and analysis of its mechanism. Page:416—419
15. Stereoselectivity in biliary excretion of trans tramadol and trans O-demethyltramadol in rats. Page:412—415
16. Effects of human recombinant interleukin-1 receptor antagonist on isolated trachea smooth muscle of the guinea pig. Page:409—411
17. High throughput screening for intercellular adhesion molecule-1 inhibitor. Page:405—408
18. Oligonucleotide uptake in hematological tumor cells is related to cellular species and proliferation. Page:401—404
19. Progress in the synthesis of diketopiperazines. Page:395—400
20. Bioequivalence of donepezil capsule and tablet in human. Page:392—394
21. Characteristics of drug-release in vitro of different dextran-dexamethasone conjugates. Page:388—391
22. Oleyl pyroglutamate for use as transdermal enhancer and its enhancing mechanism. Page:384—387
23. Studies on the formation mechanism of alginate-chitosan microcapsule and its drug-loading and release properties on macromolecular drug. Page:380—383
24. Metabolism of roxithromycin in dogs. Page:374—379
25. Study on the pharmacokinetics of scutellarin in dogs. Page:371—373
26. Determination of tanshinone IIA in rat plasma and the pharmacokinetics by RP-HPLC method. Page:368—370
27. Voltammetric behaviors of diethylstilbestrol and its determination at multi-wall carbon nanotubes modified glassy carbon electrode. Page:364—367
28. Semi-synthesis of derivatives with C-3' and C-4' trans-configuration from (+)-praeruptorin A. Page:358—363
29. Chemical constituents in the roots of Salvia przewalskii Maxim. Page:354—357
30. Identification of four new ceramides from Anthopleura pacifica. Page:350—353
31. Studies on analogues of huperzine A for treatment of senile dementia. VI. Asymmetric total synthesis of 14-nor-huperzine A and its inhibitory activity of acetylcholinesterase. Page:346—349
32. 8-(N,N-diethylamino)-n-octyl-3,4,5-trimethoxybenzoate inhibited the reduction of cerebral blood flow evoked by 5-HT and KCl in rats. Page:342—345
33. 9-(4-ethoxycarbonylphenoxy)-6,7-dimethoxy-1,2,3,4-tetrahydro acridine inhibits free radical induced rat cortical neuron cytotoxicity and cerebral ischemia injury. Page:337—341
34. Effects of potassium channel blockers on the proliferation of rat bronchial smooth muscle cells. Page:333—336
35. Regression of vascular remodeling in renovascular hypertensive rats by tetrandrine and enalapril. Page:328—332
36. Effects of sodium magnesium fructose diphosphate on free calcium concentration and nitric oxide synthase activity of ischemic synaptosome. Page:325—327
37. Platelet phospholipase A2 mRNA content changes and cDNA cloning in rat blood with bacteria infection. Page:321—324
38. Application of cationic polymer vector for gene delivery systems. Page:316—320
39. Biological characteristics of microtubule and related drug research. Page:311—315
40. Two chemotypes of Pogostemon cablin and influence of region of cultivation and harvesting time on volatile oil composition. Page:307—310
41. Preparation of solid lipid nanoparticles by solvent diffusion method. Page:302—306
42. Study on polymethacrylate nanoparticles as delivery system of antisense oligodeoxynucleotides. Page:298—301
43. Continuous in situ monitoring of the dissolution rate of solid pharmaceutical preparations using a multiple channel fiber-optic chemical sensor. Page:294—297
44. Study on Aconitum diterpenoid alkaloids from flowers of Aconitum kusnezoffi and its decoction by ESI-MS. Page:290—293
45. Determination of chlorogenic acid and eriodictyol-7-O-beta-D-glucuronide in Pyrrosia by RP-HPLC. Page:286—289
46. Determination of adenosine, rutin and quercetin in Carthamus tinctorius by HPCE. Page:283—285
47. Determination of trigonelline by HPLC and study on its pharmacokinetics. Page:279—282
48. Alkaloids from a Tibetan medicine Meconopsis quintuplinervia Regel. Page:276—278
49. Studies on the chemical constituents of the aerial part of Cimicifuga foetida L. Page:272—275
50. Two new phenylethanoid glycosides from Corallodiscus flabellata. Page:268—271
51. Synthesis and antibacterial activity of 7-(4-acylamino-thiocarbamoyl-1-piperazinyl) fluoroquinolone analogues in vitro. Page:264—267
52. Synthesis and antibacterial activity of pyridonecarboxylic acid derivatives containing 2-methyl-5-nitroimidazol. Page:260—263
53. Studies on antidiabetic effects of cortex Moutan polysaccharide-2b in type 2 diabetes mellitus rats. Page:255—259
54. Potentiation and mechanism of cisplatin-induced apoptosis by lidamycin in human hepatoma BEL-7402 cells. Page:250—254
55. Effect of lipopolysaccharide on expression of matrix metalloproteinase-9 in human synoviocyte from patients with rheumatoid arthritis. Page:245—249
56. Antioxidation properties and mechanism of action of dihydromyricetin from Ampelopsis grossedentata. Page:241—244
57. Research progress on application of drug nano-carriers. Page:236—240
58. Preparation of thrombus-targeted urokinase liposomes and its thrombolytic effect in model rats. Page:231—235
59. Studies on hypersensitivity and pharmacokinetics of paclitaxel microemulsion. Page:227—230
60. The aquation of oxaliplatin and the effect of acid. Page:223—226
61. Preparation and pharmaceutical properties of salcatonin dry powder inhalations. Page:218—222
62. HPLC-fluorescent spectrometric determination of serum mexiletine concentration after derivatization with fluram. Page:215—217
63. Enantiomeric separation of ketoprofen by HPLC using chirobiotic V CSP and vancomycin as chiral mobile phase additives. Page:211—214
64. Separation of salicylic acid drugs by aqueous and nonaqueous capillary electrophoresis with conductance detector. Page:207—210
65. Determination of donepezil in human plasma by HPLC-MS. Page:203—206
66. Studies on the lignan chemical constituents from pine needles of Pinus massoniana Lamb. Page:199—202
67. Isolation and structure identification of flavonol glycoside from Lysimachia christinae Hance. Page:196—198
68. Synthesis of a novel starch derivative and its adsorption property for creatinine. Page:191—195
69. Genotyping and species identification of Fritillaria by DNA chips. Page:185—190
70. Long-term effects of 17 beta-estradiol in promoting 45Ca uptake and mineralized bone-like tissue formation in human osteoblast-like cell lines TE85. Page:181—184
71. Ginsenoside Rg1 may protect SHSY5Y cells from apoptosis induced by MPP+ through JNK way. Page:176—180
72. Effect of atropine on the inhibition of melatonin to the unit discharges evoked in the posterior group of thalamic nuclei in cats. Page:173—175
73. Differential protein analysis in rat renal proximal tubule epithelial cells in response to acetazolamide and its relation with the inhibition of AQP1. Page:169—172
74. Study on methods and requirements for quality control of recombinant human tumor necrosis factor receptor Fc fusion protein. Page:165—168
75. Piperazinyl estrone prevents bone loss in ovariectomized rats. Page:161—164
76. Solid phase micro-extraction technique and its applications in medical analysis. Page:153—158
77. RbcL sequence analysis of Belamcanda chinensis and related medicinal plants of Iris. Page:147—152
78. Study on the hepatocytic cell targetability of liposomes. Page:143—146
79. Hypoglycemic effect of polysaccharide-coated insulin liposomes after oral administration in mice. Page:138—142
80. Preparation of cisplatin multivesicular liposomes and release of cisplatin from the liposomes in vitro. Page:133—137
81. Protective effect of 3,4-oxo-isopropylidene-shikimic acid on vascular endothelial cell injured by hydrogen peroxide. Page:897—899
82. Stereoselectivity in absorption of trans tramadol in rat intestine. Page:893—896
83. Effects of TNF-alpha receptor blocking peptide on adjuvant arthritis in rats. Page:889—892
84. Relationship between neurotoxicity of 6-hydroxydopamine and glutamate transport. Page:885—888
85. Effects of 7-oxo-DHEA treatment on the immunoreactivity of BALB/c mice subjected to chronic mild stress. Page:881—884
86. Advances in studies on eudistomin marine alkaloids. Page:876—880
87. Molecular identification of six medicinal Curcuma plants produced in Sichuan: evidence from plastid trnK gene sequences. Page:871—875
88. Effect of RMP-7 and its derivatives on the transportation of liposome into the brain. Page:867—870
89. Secondary structure of insulin encapsulated within liposomes. Page:863—866
90. Studies on formulations of Panax notoginsenosides for intranasal administration. Page:859—862
91. Preperation of terbutaline sulphate pulsatile release tablet and mechanism elucidation. Page:854—858
92. Pharmacokinetics of sibutramine hydrochloride in Chinese healthy volunteers. Page:850—853
93. Determination of ginkgolic acids in Ginkgo biloba extract and its preparations by high performance liquid chromatography. Page:846—849
94. Determination of the inhibitory activity of angiotensin-converting enzyme inhibitor captopril by high performance capillary electrophoresis. Page:843—845
95. Study on molecular chain morphology and chain parameters of konjac glucomannan. Page:838—842
96. Studies on the chemical constituents of a fungus producing perylenequinones. Page:834—837
97. Antagonistic effect of myricetin on platelet activing factor. Page:831—833
98. Structure-based design, synthesis and evaluation of bioactivity of anti-P-gp peptide mimetic. Page:826—830
99. Cardioprotective effect and influence on NOS expression of Montelukast sodium in rats. Page:821—825
100. Baicalein selectively induce apoptosis in human leukemia K562 cells. Page:817—820
101. Effect of ouabain on the aortic rings of guinea pig and its interactions with Ca2+, norepinephrine. Page:813—816
102. Effect of indomethacin on expression of interleukin-6 caused by lipopolysaccharide in rheumatoid arthritic patients' synoviocyte. Page:809—812
103. Effects of 3-substituted aryl oxindole(PH II-7) on cell cycle of tumor cells. Page:805—808
104. Inhibitory effect of egg white lysozyme on ceftazidime-induced release of endotoxin from Pseudomonas aeruginosa. Page:801—804
105. Current status of camptothecin derivatives as natural antitumor agents. Page:715—720
106. Stability studies of sulfated polyguluronic acid ester. Page:711—714
107. Studies on diclofenac sodium pulsatile release pellets. Page:707—710
108. Evaluation of interaction between drugs and ordered phospholipid membrane by immobilized artificial membrane chromatography. Page:702—706
109. Cationic lipid and polyethylene glycol enhance liposomes-mediated cell transfection and increase the fluidity of liposomes membranes. Page:698—701
110. Analysis of the response factors of different quinolones detected by evaporative light-scattering detector. Page:695—697
111. Nucleoside from Cordyceps kyushuensis and the distribution of two active components in its different parts. Page:690—694
112. Quality control of recombinant adeno-associated virus type 2/human blood coagulation factor IX. Page:684—689
113. Studies on the chemical constituents of Angelica sinensis. Page:680—683
114. A new alkaloid from Opuntia vulgaris. Page:677—679
115. Synthesis and anti-inflammatory activity of alpha-substituted p-(methanesulfonyl)phenylpropenamides. Page:671—676
116. Synthesis and antifungal activity of 1-(1,2,4-triazolyl-1H-1-yl)-2-(2,4-diflurophenyl)-3-(4-substituted benzyl-1-piperazinyl)-2-propanols. Page:665—670
117. Effects of interleukin-1 receptor antagonist on the apoptosis of eosinophil in guinea pig with asthma. Page:661—664
118. Effects of phenolic alkaloids of Menispermum dauricum on the hemodynamics and coronary circulation in anesthetized dog. Page:658—660
119. Enzyme kinetics of clausenamide enantiomers in rat liver microsomes. Page:654—657
120. Evodiamine induces A375-S2 cell death through two different pathways. Page:650—653
121. Pharmacokinetics of genistein in beagle dogs. Page:646—649
122. Antithrombotic effects of morpholine and piperazine ring derivatives and their molecular mechanism. Page:641—645
123. Application of biochip, genomics and proteomics in drug research and development. Page:795—800
124. Comparative study of lipophilicity from immobilized artificial chromatography and n-octanol/buffer systems. Page:791—794
125. Preparation of bovine serum albumin nanoparticles surface-modified with glycyrrhizin. Page:787—790
126. Establishment and application of in situ perfused pig ear model for percutaneous absorption. Page:783—786
127. Precipitation reaction between berberine and rheinic acid by capillary electrophoresis. Page:779—782
128. Study on pharmacokinetics of scutellarin in rabbits. Page:775—778
129. Determination of danshensu in urine and its pharmacokinetics in human. Page:771—774
130. NMR studies on cetirizine hydrochloride. Page:767—770
131. Studies on the chemical constituents from the aerial parts of Cimicifuga dahurica. Page:763—766
132. Chemical constituents of Cyanotis arachnoidea. Page:760—762
133. Synthesis and in vitro antibacterial activities of new 3,5-disubstituted oxazolidinone compounds. Page:754—759
134. Synthesis and pharmacology of 8-amino-3-(tetrahydro-2-furanyl)methyl benzomorphan. Page:748—753
135. Protection of organic trauma in sinoaortic-denervated rats treated with fosinopril. Page:743—747
136. Effects of caspases on cerebromicrovascular endothelial cell apoptosis induced by hypoxia. Page:739—742
137. Culture of neural stem cells from cerebral cortex of rat embryo and effects of drugs on the proliferation ability of stem cells. Page:735—738
138. Novobiocin inhibits angiogenesis and shows synergistic effect with vincristine. Page:731—734
139. Effect of esculentoside A on cellular adhesion. Page:728—730
140. Protective effects of 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino) propane hydrochloride(DDPH) on brain ischemia injury in rats. Page:725—727
141. mRNA expression alteration of two-pore potassium channels in the brain of beta-amyloid peptide25-35-induced memory impaired rats. Page:721—724
142. Preparation of sustained-release nitrendipine microspheres with a solid dispersed structure in liquid system. Page:634—638
143. Cutaneous permeation kinetics and pharmacodynamics of topical lidocaine gel in rat. Page:631—633
144. Kidney-targeting characteristics of N-acetyl-L-glutamic prednisolone prodrug. Page:627—630
145. Preparation of solid lipid nanoparticles by microemulsion technique. Page:624—626
146. Sandwiched osmotic pump tablet for controlled release of water-insoluble drug. Page:620—623
147. Determination of first-order structure of somatostatin by electrospray ionization mass spectrometry. Page:617—619
148. Antibody sandwich enzyme-linked immunoadsorbent assay for determination of recombinant E. coli L-asparaginase in rat plasma and its pharmacokinetics. Page:613—616
149. Characterization of N-glycan mapping of bioengineering recombinant erythropoietin by capillary electrophoresis with laser-induced fluorescence. Page:609—612
150. Studies on differences of pharmacokinetic behavior and tissue distribution of nimodipine and its two enantiomers in rats using achiral and chiral liquid chromatography. Page:603—608
151. Studies on flavonoid constituents of Caragana intermediia. Page:599—602
152. A novel phlegmariurine type alkaloid from Huperzia serrata (Thunb.) Trev. Page:596—598
153. Studies on chemical constituents of Hedysarum polybotrys. Page:592—595
154. Synthesis and nNOS inhibitory activity of benzenealkyl isothiourea compounds. Page:586—591
155. Inhibition of MCP-1 mRNA expression by propylene glycol mannate sulfate in hyperlipidemic rat aorta. Page:582—585
156. Comparison of the antagonistic effects of 6 beta-naltrexol and naltrexone against morphine analgesia. Page:578—581
157. Effects of quercetin on platelet-endothelial cell adhesion and their expression of adhesion molecules. Page:574—577
158. Pharmacokinetics of osthole in rabbits. Page:571—573
159. Experimental chemotherapy against xenografts derived from multidrug resistant KBv200 cells and parental drug-sensitive KB cells in nude mice by annonaceous acetogenin 89-2. Page:565—570
160. Protective effects and mechanism of action of aspirin on focal cerebral ischemia-reperfusion in rats. Page:561—564
161. Microbial transformation of sinenxan A, a rich constituent in callus cultures of Taxus. Page:555—558
162. Preparation of acyclovir liposome and study on its stability. Page:552—554
163. Spectrophotometry on measuring the size of liposomes. Page:547—551
164. Simultaneous determination of 3 kinds of components in Gardenia by high-performance liquid chromatography under different UV-vis wave length. Page:543—546
165. Highly-accurate nephelometric titrimetry. Page:537—542
166. HPLC-ELSD determination of triterpenoids and triterpenoid saponins in Ilex pupurea leaves. Page:534—536
167. Resonance Rayleigh scattering spectra of berberine-tetraphenylboron association nanoparticle and its analytical application. Page:530—533
168. Studies on the chemical constituents of Dendrobium fimbriatum. Page:526—529
169. The isolation and identification of a new alpha-pyrone from Opuntia dillenii. Page:523—525
170. Studies on the lignans from Patrinia scabra. Page:520—522
171. Antitumor effects of the immunoconjugate composed of lidamycin and monoclonal antibody 3G11. Page:515—519
172. Studies on the simvastatin effect on the artery of atherosclerotic rabbit using proteomics approaches. Page:511—514
173. Synthesis of propenamides with anti-malarial activities and 3D-QSAR study. Page:505—510
174. Inhibition of dexamethasone, indomethacin and resveratrol on matrix metalloproteinase-9 and the mechanism of inhibition. Page:501—504
175. Investigations on the molecular mechanisms of saponins from Anemarrhena asphodeloides Bunge using oligonucleotide microarrays. Page:496—500
176. Effects of cyclosporin A aerosol on airway hyperresponsiveness in rats. Page:492—495
177. Inhibition of magnesium lithospermate B on the c-Jun N-terminal kinase 3 mRNA expression in cardiomyocytes encountered ischemia/reperfusion injury. Page:487—491
178. Several strategic consideration for the modernization of Chinese materia medica. Page:485—486
179. Microbial biopharmaceuticals and antibody-based drugs--promising for new drug discovery and development. Page:483—484
180. Immobilized artificial membrane chromatography and its application in biopharmaceutics. Page:475—480
181. Study on the metabolite of stilbene glucoside in mice by liquid chromatography tandem-mass spectrometry. Page:968—970
182. Unitary-core osmotic pump tablet for controlled release of water-insoluble drug. Page:966—967
183. Synthesis of prodrugs of tacrine hydrochloride and evaluation of the stability and biodistribution in mice. Page:962—965
184. Study on pulmonary delivery of peptide drugs in rats: effects of absorption enhancers on cellular membrane fluidity. Page:957—961
185. Studies on gastrointestinal absorption enhancement effect and mechanism of sodium N-8-(2-hydroxybenzyl)amino caprylate to insulin solution. Page:953—956
186. Analysis of impurity in caderofloxacin. Page:950—952
187. Effects of changes in conformation and configuration of N-containing compounds on NMR spactra. Page:946—949
188. Study on bioequivalence of domestic bambuterol capsules and imported tablets by high performance capillary zone electrophoresis. Page:942—945
189. Ginkgo flavones in in vitro metabolism and its clinical application. Page:938—941
190. Structure identification of jujuboside E. Page:934—937
191. Daviditin B from Swertia davidi Franch. Page:931—933
192. Isolation and structure identification of lignans from pine needles of pinus massoniana Lamb. Page:927—930
193. Chemical constituents of Ligularia dictyoneura. Page:924—926
194. Synthesis and antitumor activity of the derivatives of cephalotaxine and drupacine. Page:919—923
195. Synthesis and radiopharmacology of S-(2-18F-fluoroethyl)-L-methionine for tumor imaging. Page:915—918
196. Inhibitory action of berberine on glucose absorption. Page:911—914
197. Determination of daurisoline in rabbit plasma and study on its pharmacokinetics. Page:908—910
198. Effects of conjugated linoleic acid on obese MSG mice with insulin resistance. Page:904—907
199. Antagonistic effect of sodium ferulate on glycerol-induced renal oxidative injury in mice. Page:900—903
200. Study on separation of sulfonamides by capillary high-performance liquid chromatography and electrochromatography. Page:129—132
201. Determination of 9-nitrocamptothecin in rat plasma and tissues by high performance liquid chromatography. Page:124—128
202. Determination of adefovir in monkey plasma by liquid chromatography-tandem mass spectrometry. Page:120—123
203. Isolation and structural identification of phenylethanoid glycosides from Corallodiscus flabellata. Page:116—119
204. A new chromone glycoside from Cassia siamea lam. Page:113—115
205. Prognosticating the region-selectivity in the O-methylation reaction of erythromycins by conformational search model. Page:108—112
206. Protective effect of puerarin on vascular endothelial cell apoptosis induced by chemical hypoxia in vitro. Page:103—107
207. Effect of ginkgolide B on platelet-activating factor induced activation of rat polymorphonuclear leukocytes. Page:98—102
208. Comparison of the effects of polysaccharides from wood-cultured and bag-cultured Ganoderma lucidum on murine spleen lymphocyte proliferation in vitro. Page:92—97
209. A new vomiting animal model--mink. Page:89—91
210. Antioxidant effect of Ganoderma polysaccharide peptide. Page:85—88
211. Resveratrol promote permeability transition pore opening mediated by Ca2+. Page:81—84
212. Effects of sodium magnesium fructose diphosphate on free calcium concentration and nitric oxide synthase activity of ischemic synaptosome Page:325—327
213. 9-(4-Ethoxycarbonylphenoxy)-6,7-dimethoxy-1,2,3,4-tetrahydro acridine inhibits free radical induced rat cortical neuron cytotoxicity and cerebral ischemia injury Page:337—341