1. Basic research of biotherapy for osteosarcoma |
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2. Making Monoclonal Antibodies by Phage Antibody Libraries |
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3. Experimental Study on the Anti-tumor Mechanism of Interleukin-6 |
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4. Experimental Study on the Immunoprotective Effect and Mechanism of Action of Specific Active Immunization with Tumor Cell Vaccine |
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5. Expression and Characterization of Human/Murine Chimeric Antibodies with Specificity for CD3 Antigen |
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6. Construction of Anti-CD3 Human/Murine Chimeric Antibody Genes for Expression in Mammalian Cells |
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7. Targeting T Lymphocytes by Bi-specific Monoclonal Antibodies to Eliminate Tumor Cells in Bone Marrow |
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8. Antitumor Activity of the Conjugates Composed of C1027, an Anticancer Antibiotic, and Monoclonal Antibody |
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9. The Quality Control and Targeting Studies of Anti-hepatoma Monoclonal Antibodies |
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10. Application of the Monoclonal Antibody 3H11 Against Gastric Cancer |
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11. The Novel Procedures to Increase the Expression Efficiency of Recombinant Human IL-6 in Eukaryotic Cells |
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12. Analysis of Efficacy of TIL Therapy with Different Transfer Ways |
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13. Gene Therapy of Mice Melanoma by HSV-tk/ACV System |
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14. Effects of G-CSF Gene Therapy bn the Number and Functions of Peripheral Neutrophils of Colon Adenocarcinoma-Bearing Mice Receiving High-Dose Chemotherapy |
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15. Antitumor Effects of G-CSF Gene Therapy on Colon Adenocarcinoma-Bearing Mice Receiving High-Dose Chemotherapy |
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16. Combined Use of IL-2 and IL-7 Augments the in vitro Growth of T Lymphocytes with Maintenance of Functional Specificity |
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17. Construction of cDNA Expression Library from Lung Cancer Cells |
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18. Repertoire Antibody Library Constructed from Human Peripheral Blood Lymphocytes with in vitro Immunization with Colorectal Carcinoma-Associated Antigen |
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19. Comparison of Apoptosis Fluorescence Staining Assay and MIT Assay in the Antitumor Drugs Sensitivity Test |
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20. Experimental Study on TNF-a Gene Expression and Anti-Pulmonary Metastases of Macrophages Activated by New Castle Disease Virus |
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21. The Therapeutic Effect of Short Term Administration of IFN-? on Non-Small Cell Lung Carcinoma |
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22. Effect of Retroviral Vector-Mediated IL6/IL2 Fused Gene Transduction on B16 Melanoma Cells Adhesive and Metastatic Potential |
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23. The Antitumor Effects of Recombinant Human Fusion Protein GM-CSF/LIF in vitro |
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24. Reversal of Drug Sensitivity in Multidrug Resistant Human Hepatocarcinoma Cells BEL-7402/DOX by a Ribozyme which can Cleave Human MDR1 mRNA |
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25. The Role of Recombinant p53 Adenovirus Vector in the Growth of Lung Adenocarcinoma Cell Line GLC-82 |
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26. Study on the Retrovirus Mediated Transfer of GM-CSF cDNA in Hematopoietic Progenitor Cells |
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27. Expression of Exogenous r-Interferon Genes in Human HepatoceUuIar Carcinoma Cells Following Retroviral Transduction |
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28. Introduction of Rb, p53, p16 and H-ras Antisense UNA Suppresses Tumorigenicity in Human Gastric Cancer Cell Lines |
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29. Study on the Antigens of Tumor FBL-3: I . Analysis of Peptide Antigens from Peptides Pool of Tumor Cells by Acid Elution |
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30. Construction and Expression of 3H11 Human-Mouse Chimeric Antibody Directed against Human Gastric Cancer |
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31. The Effect of Anti-Hepatocellular Carcinoma of HSV-tk Gene Therapy Mediated by Cationic Liposome in vitro and in vivo |
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32. The Expression of Human Papillomavirus DNA in Human Laryngeal Carcinoma Cells |
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33. Physical and Chemical Characteristics and Peptide Mapping of Recombinant Human GM-CSF |
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34. In vitro Observation on the Immunological Characters of IFN-? Induced, IL-2 Gene-Modified Human Primary Fibroblasts |
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35. Dependence of Transmembrane TNF-? Bioactivity on Biomembrane |
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36. Anti- Tumor Effect of Vaccination with Irradiation Tumor Cells Transduced with Mouse Interferon-Gamma Gene |
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37. Transduction of B7-1 Gene into Melanoma Abrogates IFN-? Induced Increase in Metastatic Potential |
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38. Determination Method of rhTNF-? Bioassay and Mechanism of rhTNF-? on Human Leukmic HL-60 Cells |
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39. Effects of rhIL-17 on Differentiation and Development of Murine Hematopoietic Progenitors and Human Cord Blood CD34+ Stem Cells |
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40. The Therapeutic Effects of Intratumoral Injection with MHC Class Ⅱ Gene on Tumor-Bearing Mice |
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41. Construction of Eukaryotic Expression Vector for Tumor-Associated Gene SNC90 and Transfection into Cancer Cells |
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42. Anergy and Characteristics of Human T Cells Induced by Combination with B7-1 mAb and CsA |
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43. Cloning of Three MAGE Genes from Hepatocellular Carcinoma |
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44. The Expression of Muti-Genes Via a Recombinant Adenovirus and Their Effects of Inducing Apoptosis on Lung Cancer Cells |
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45. Clinical Trial Phase Ⅱ on rhG-CSF in Prevention of Neutropenia after Chemotherapy |
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46. A Randomized and Controlled Study of rhGM-CSF on Leucopenia Induced by Chemotherapy on Cancer Patients |
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47. Preparation of Anti-EGFR Monoclonal Antibody Immunoconjugate (EQ75-ADR) and It's Inhibitory Effect on Human Epidermoid Carcinoma |
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48. Reversion of Transforming Growth Factor ?_2 Mediated Immunosuppression in Lung Cancer by Icarrin |
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49. in vivo and in vitro Anti-Tumor Effeciency of B16 Melanoma HSP-Antigen Peptide Complex (HAC) |
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50. Mutagenesis of Transgenic Human Lung Adenocarcinoma Cell Line SPC-A-1/IL-2 |
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51. in vitro Expansion and Differentiation of Cord Blood Hemotopoietic Cells |
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52. The Control of Apoptosis and Drug Resistance in Ovarian Cancer Cells Which Overexpressed bcl-2 |
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53. Antitumor Responses Induced by Recombinant Vaccinia Viruses Expressing p53 and B7 |
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54. Antagonism Function of Anti-Sense Nucleic Acids on IL-6 Signal Transduction in Myeloma Cells |
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55. Inhibitory Effect of Liver Metastasis of Human Colon Cancer by TNP-470 in Combination with 5-FU |
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56. Cloning of Fab Gene of an Anti-Human Bladder Cancer Monoclonal Antibody and Its Expression in E. coli |
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57. The Biological Characteristics in vitro and Anti-Tumor Effect in vivo of Lung Cancer Cells Infected with Recombinant Adenovirus Expressing hTNF-? |
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58. Expression and Purification of Recombinant Human Endostatin |
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59. Effect of Buthionine Sulfoximine on DAAO/D-Ala System Killing K562e Cells |
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60. The Influence of Tumor-Derived Heat Shock Protein 70 on the Expression of Thl Type Cytokines of Tumor-Bearing Mice |
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61. Killing Effect of HSV-tk, hrIL-2 and hrTNF-? Fusion Genes on Hep-2 Human Laryngocarcinoma Cell Lines in vitro |
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62. Transferring Novel Gene into Human Hematopoietic Cells by Adeno-Associated Virus |
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63. Proliferation and Immunophenotypic Analysis of CD3AK Cells Derived from Lymph Node |
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64. Cytotoxicity of Hepatocellular Carcinoma Cells Induced by ICE Gene Transfetion in Combination with Antitumor Chemicals in vitro |
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65. Expression of Human T Cell Receptor ? Chain Gene in Insect Cell |
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66. Cloning and Identification of Fd and Light Chain Genes of MAb HAb18 against Human Hepatoma |
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67. Synergistic Inhibition of TNP-470 and Recombinant Human Endostatin on the Growth of Mice Lung Adenocarcinoma LA795 |
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68. Construction of Recombinant Adenoviral Vector Carrying the Human BMP-2 Gene with the Technology of in vitro Ligation |
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69. The Specific High Expression of Apoptosis-Inducing BAX Gene Driven by Human Cyclooxygenase-2 Promoter in Ovarian Cancer Cell Line |
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70. Induction of Apoptosis in U343 Cell Line by a Novel Anti-Human DR5 Monoclonal Antibody |
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71. Effect on Cytotoxicity by Blocking ERCC1 Gene Expression in Ovarian Cancer Cell Lines |
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72. Anti-Tumor Study of pOSP1-HSVtk Gene Therapy by Polyethylenimine Mediated Transfection in Ovarian Cancer |
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73. Growth Inhibition of Tumor by Recombinant SEA |
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74. Construction of Recombinant Mice Factor Ⅶ-pPIC9K Vector and Expression in Pichia |
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75. Arsenic trioxide induces apoptosis of gastric cancer cell AGS and influences STAT3 and VEGF expression |
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76. hMLH1 protein expression in esophagus squamous cell carcinoma, esophagus atypical hyperplasia, and normal esophagus tissues |
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77. Pathological changes of human hepatocellular carcinoma after continuous passaging in nude mice |
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78. Expression of histone deacetyase 4 in human liver carcinoma cell line Bel-7402 and its significance |
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79. Inhibitory effect of antisense human telomerase RNA(hTR) gene on hepatocellular carcinoma cells |
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80. Tumor vessel-specific antibody ScFvH1: Targeting efficiency and anti-tumor ability |
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81. Recombinant mutant human-TNF in reversing drug-resistance in ovarian cancer cell line SKOV3/DDP and the related mechanism |
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82. PUMA gene transfection increases sensitivity of pancreatic cancer cell line AsPC-1 to 5-FU-induced apoptosis |
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83. Lentivirus mediated RNA interference inhibits mesothelin expression in ovarian cancer cells and cell proliferation |
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84. Inhibitory effect of endostatin gene on transplanted osteosarcoma in nude mice |
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85. Inhibitory effect of recombinant adenovirus-mediated mouse endostatin on pulmonary metastasis of osteosarcoma cell line MG-63 in nude mice |
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86. Expression of ATPase F1? in human colorectal cancer tissues and cell line and its clinical significance |
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87. HER-2 RNA interference improves sensitivity of breast cancer cells to chemotherapy in vitro and in vivo |
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88. Immunogenicities of apoptotic ovarian cancer cells induced by paclitaxel combined with cisplatin |
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89. Advances in molecular targeted therapy and biochemotherapy in oncology |
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90. In Vivo Effects of IL-3, IL-6 and IL-4, Alone and in Combination with G-CSF and GM-CSF, on Hematopoietic Reconstitution Following Murine Allogeneic Bone Marrow Transplantation |
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91. The Cytotoxic Effects on Gastric Cancer Mediated by Bi-specific Antibodies |
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92. High-Efficiency Retroviral Vector Containing Human Mutated Dihydrofolate Reductase cDNA and Its Expression in Murine Hematopoietic Progenitor Cells |
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93. Induction of Tumor Cell Apoptosis by Adenovirus-Mediated E. coli Cyto-sine Deaminase Gene Transfection and Its Bystander eftect |
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94. More Efficieat Induction of Autitumor Response by Combined Suicide Gene and Interleukin 2 Gene Transfer Mediated by Recombinant Aden-ovirus |
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95. The Immological Rejection Activated by Human Heptocarcinoma Transferred with Murine H-2K~b Gene |
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96. Strategy on Enhancement of bFGF Gene Expression and Purification of Its Products |
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97. Immunotherapeutic Effects of Elemene Combo Tumor Cell Vaccine on Hca-F and Changes of IL-10 and IL-12 Secretion by Splenocytes of Treated Mice |
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98. Combination with Histamine and LAK/IL-2 Therapy for the Treatment of Metastatic Melanoma |
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99. Comparison Researches on the Mode of Cell Death Induced by NDV-Strain Changchun and NDV-Strain Siping |
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100. The Effects of Arsenite Trioxide in Various Concentrations on the Esophageal Carcinoma Cell Line |
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101. OK-432 Induced IL-12 and Th1 Cytokines Production in Tumor Bearing Mice |
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102. VP22 Enhanced Intercellular Trafficking of HSV Thymidine Kinase Promoted an Effective Cell Killing Effect at Lower Concentration of Ganciclovir |
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103. Preparation,purification and biological function of fusion protein of ovalbumin and HSP70-1ike protein 1 |
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104. Inhibitory effect of siRNA on HPA gene expression in SKOV3 cells |
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105. Influence of RNA interference on expression of Aurora-A in human ovarian cancer cells and on cell proliferation |
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106. Recombinant fibronectin polypeptide CH50 improves positive immune regulation in tumor microenvironment |
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107. FK228 blocks cells survival signal pathways and induces apoptosis of prostate cancer DU145 cells |
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