Volume: 25 Issue: 1

1. Applications of model-informed drug development (MIDD) on new drug research and development Page:1—8
2. Personalizing pertuzumab and trastuzumab dosing regimens for adjuvant treatment of HER2-positive breast cancer Page:10—21
3. Application of biomarkers in clinical development of biologics and bioanalytical strategies Page:22—31
4. Development of therapeutic biologics in cancer treatment Page:32—43
5. Risk management of biological agents in phase I clinical trials: Case sharing Page:44—48
6. Agkistrodon halys venom platelet inhibitor inhibits GPVI expression and changes hemorheology in rats with acute myocardial ischemia reperfusion injury Page:49—54
7. Silencing carbonic anhydrase 1 inhibits the proliferation, invasion and migration of A549 cells in lung cancer Page:55—60
8. Mechanism of turmeric in treating asthma based on network pharmacology Page:61—67
9. Bioequivalence of olmesartan medoxomil tablets in Chinese healthy subjects in fasting state Page:68—74
10. Optimal dosage of dexmedetomidine on prevention of agitation induced by sevoflurane anesthesia in children Page:75—80
11. N-acetylcysteine combined with pulmonary surfactant alleviates neonatal severe fetus seizure syndrome through regulating fetal inflammatory factors and oxygenation Page:81—86
12. Ginsenoside Rg1 in the treatment of nonalcoholic fatty liver disease Page:87—93
13. Correlation between vitamin D and thyroid disease Page:94—100
14. Neurobiological factors of trait anxiety and its influences on individual cognitive performance Page:101—106
15. Progress in the treatment of multiple myeloma Page:107—116
16. Experience in quality control of clinical trials of DMARDs Page:117—120