Intravitreal injection of bevacizumab before pars plana vitrectomy in tractional retinal detachment
- Collective Name:Philippine Journal of Ophthalmology (PJO)
- Publication Type:Journal Article
- MeSH:
Bevacizumab
- From:
Philippine Journal of Ophthalmology
2009;34(2):1-
- CountryPhilippines
- Language:English
-
Abstract:
Objective:To describe the role of preoperative intravitreal bevacizumab in patients with tractional retinal detachment undergoing pars plana vitrectomy.
Methods:Five eyes of 5 patients with tractional retinal detachment and excessive fibrovascular membrane secondary to proliferative diabetic retinopathy received a single dose of 1.25 mg of intravitreal bevacizumab 5 to 7 days prior to the scheduled pars plana vitrectomy. Pre- and postinjection, intra- and postoperative fundus photos were taken. Intraoperative outcomes were evaluated based on change in the severity of vitreous and intraretinal hemorrhage, change in size of vessel caliber, amount of neovascularization, and the variability of the size of the fibrovascular membrane.
Results:The amount of hemorrhage, vessel caliber, neovascularization, and fibrovascular membrane were decreased significantly. Minimal bleeding during dissection of the fibrovascular membrane was noted.
Conclusion:Intravitreal injection of bevacizumab showed promise as an adjunct in the surgical treatment of tractional retinal detachment secondary to proliferative diabetic retinopathy.
