Healthy lifestyle interventions for childhood and adolescent cancer survivors: a systematic review and meta-analysis
10.4094/chnr.2023.29.2.111
- Author:
Kyung-Ah KANG
1
;
Suk Jung HAN
;
Jiyoung CHUN
;
Hyun-Yong KIM
;
Yerin OH
;
Heejin YOON
Author Information
1. Professor, College of Nursing, Sahmyook University, Seoul, Korea
- Publication Type:Review Article
- From:Child Health Nursing Research
2023;29(2):111-127
- CountryRepublic of Korea
- Language:English
-
Abstract:
Purpose:This study investigated the effects of healthy lifestyle interventions (HLSIs) on health-related quality of life (HR-QoL) in childhood and adolescent cancer survivors (CACS).
Methods:Major databases were searched for English-language original articles published between January 1, 2000 and May 2, 2021. Randomized controlled trials (RCTs) and non-RCTs were included. Quality was assessed using the revised Cochrane risk-of-bias tool, and a meta-analysis was conducted using RevMan 5.3 software.
Results:Nineteen studies were included. Significant effects on HR-QoL were found for interventions using a multi-modal approach (exercise and education) (d=-0.46; 95% confidence interval [CI]=-0.84 to -0.07, p=.02), lasting not less than 6 months (d=-0.72; 95% CI=-1.15 to -0.29, p=.0010), and using a group approach (d=-0.46; 95% CI=-0.85 to -0.06, p=.02). Self-efficacy showed significant effects when HLSIs provided health education only (d=-0.55; 95% CI=-0.92 to -0.18; p=.003), lasted for less than 6 months (d=-0.40; 95% CI=-0.69 to -0.11, p=.006), and were conducted individually (d=-0.55; 95% CI=-0.92 to -0.18, p=.003). The physical outcomes (physical activity, fatigue, exercise capacity-VO2, exercise capacity-upper body, body mass index) revealed no statistical significance.
Conclusion:Areas of HLSIs for CACS requiring further study were identified, and needs and directions of research for holistic health management were suggested.
