Practical issues in CAR T-cell therapy
- Author:
Ja Min BYUN
1
Author Information
- Publication Type:REVIEW ARTICLE
- From:Blood Research 2023;58(S1):11-12
- CountryRepublic of Korea
- Language:English
- Abstract: Chimeric antigen receptor (CAR) T-cell therapy presents a revolutionary advancement in personalized cancer treatment. During the production process, the patient's own T-cells are genetically engineered to express a synthetic receptor that binds to a tumor antigen. CAR T-cells are then expanded for clinical use and infused back into the patient's body to attack cancer cells. Although CAR T-cell therapy is considered a major breakthrough in cancer immunotherapy, it is not without limitations. In this review, we discuss the barriers to effective CAR T-cell therapy in Korea.
