Nodular scalp mass as the first presentation of pulmonary large cell neuroendocrine carcinoma: a case report
- Author:
Hong Won LEE
1
;
Young Joong HWANG
;
Sung Gyun JUNG
;
In Pyo HONG
Author Information
- Publication Type:Case Report
- From:Archives of Craniofacial Surgery 2023;24(5):240-243
- CountryRepublic of Korea
- Language:English
- Abstract: Metastasis of lung cancer to the skin is uncommon, presenting in 0.22% to 12% of lung cancer patients, and it is extremely rare for skin metastasis to be the first clinical manifestation of lung cancer. In the few cases where skin metastasis has been reported as the first sign of lung cancer, the patients were typically heavy smokers or had preexisting respiratory diseases and symptoms. This prompted clinicians to consider skin metastasis of a pulmonary malignancy. Large cell neuroendocrine carcinoma (LCNEC) is a rare type of lung cancer that accounts for approximately 3% of lung cancers. LCNEC mainly metastasizes to visceral organs, such as the liver, bone, and brain, and it only shows metastasis to the skin in very rare cases. Herein, we report an unusual case of a metastatic skin lesion as the first sign of primary pulmonary LCNEC, in a 63-year-old woman with no pulmonary symptoms or personal history of smoking or pulmonary disease.
