Ventilator support in the pretransplant period predisposes early graft failure after deceased donor liver transplantation
10.4174/astr.2023.105.3.141
- Author:
Nuri LEE
1
;
Sora CHA
;
Jongman KIM
;
Yunmi LEE
;
Enjin KANG
;
Hyun Jung KIM
;
Seung Hui HONG
;
Jinsoo RHU
;
Gyu-Seong CHOI
;
Jae-Won JOH
Author Information
1. Department of Surgery, Veterans Health Service Medical Center, Seoul, Korea
- Publication Type:ORIGINAL ARTICLE
- From:Annals of Surgical Treatment and Research
2023;105(3):141-147
- CountryRepublic of Korea
- Language:English
-
Abstract:
Purpose:Deceased donor liver transplantation (DDLT) recipients in Korea are generally sicker due to an increasing organ shortage. In the present study, the risk factors for early 30-day liver graft failure after DDLT were identified.
Methods:From August 2017 to February 2021, 265 adult DDLTs were performed. The characteristics of patients with and without 30-day graft failure were compared.
Results:Liver graft failure occurred in 11 patients (17.7%) after DDLT. Baseline and perioperative characteristics of donors and recipients were not statistically significantly different between the 2 groups. The cumulative graft and overall survival rates at 6 months were 83.9% and 88.7%, respectively. Multivariate analysis showed ventilator support in the pretransplant period was a predisposing factor for 30-day graft failure after DDLT.
Conclusion:Present study indicates that cautious decision is required when allocating DDLT in critically ill patients on mechanical ventilatory support.
