Clinical impact of C-reactive protein to albumin ratio of the 7th postoperative day on prognosis after laparoscopic colorectal cancer surgery
10.3393/ac.2022.00234.0033
- Author:
Masahiro KATAOKA
1
;
Kuniyuki GOMI
;
Ken ICHIOKA
;
Takuya IGUCHI
;
Tomoki SHIROTA
;
Arano MAKINO
;
Ko SHIMADA
;
Kiyotomi MARUYAMA
;
Motohiro MIHARA
;
Shoji KAJIKAWA
Author Information
1. Department of Surgery, Suwa Red Cross Hospital, Nagano, Japan
- Publication Type:Original Article
- From:Annals of Coloproctology
2023;39(4):315-325
- CountryRepublic of Korea
- Language:English
-
Abstract:
Purpose:C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, postoperative day (POD) 1, and POD 7 CARs and the prognosis of patients with colorectal cancer (CRC).
Methods:Three hundred twenty patients with CRC who underwent laparoscopic radical resection between May 2011 and December 2016 were enrolled. Patients were selected into 2 groups, high CAR and low CAR (n=72/group), based on preoperative, POD 1, and POD 7 CARs. The relapse-free survival (RFS) and overall survival (OS) were compared between groups using propensity score matching.
Results:The high CAR group had a significantly worse RFS (P<0.001) and OS (P=0.002) at POD 7 than those in the low CAR group. However, in preoperative and POD 1 analysis, no differences were observed.
Conclusion:In patients with CRC, CAR of POD 7 was a significant prognostic factor.
