A simulating method for dripping process of Ginkgo biloba leaf dripping pills based on computational fluid dynamics technology
10.16438/j.0513-4870.2023-0138
- VernacularTitle:一种基于计算流体动力学技术的银杏叶滴丸滴制过程仿真方法
- Author:
Xiao-ping WANG
;
Hai-bin QU
- Publication Type:Research Article
- Keywords:
simulating method;
computational fluid dynamics technology;
critical material attribute;
critical process parameter;
italic>Ginkgo biloba leaf dripping pill
- From:
Acta Pharmaceutica Sinica
2023;58(10):2909-2913
- CountryChina
- Language:Chinese
-
Abstract:
A simulating method for dripping process of Ginkgo biloba leaf dripping pills based on computational fluid dynamics was constructed. Ginkgo biloba leaf dripping pills was explored as the experimental subject to simulate the dripping process based on FLOW-3D software. The dripping process was simulated through the derivation of the governing equations, the selection of the models, and simulation parameters. Firstly, the droplet morphologies and drop speeds under different liquid viscosity were simulated. It was found that with the increase of the liquid viscosity, the drop speed decreased and the difficulty of droplet preparation gradually increased. The simulation results were consistent with the experiment results. Secondly, the droplet morphologies at different drop speeds were investigated and verified by experiments. It was found that the simulation results had a good correlation with the experiment results. The results shown that the viscosity of the liquid was the critical material attribute, and the drop speed was the critical process parameter, according to the droplet morphology. The establishment of the simulation method can deepen the understanding of the dripping process and provide a reference for the selection of raw materials and process parameters.
