Recent advances of pharmaceutical 3D printing extrusion molding technology

VernacularTitle:3D打印挤出成型技术的药学研究进展
Author: Ke ZHANG ¹ ; Dao-yi ZHENG ¹ ; An-ran LI ² ; Si-yuan LIU ¹ ; Zhi-jun WANG ² ; Yu CHEN ² ; Jia-li YU ¹ ; Yuan GAO ² ; Jian-jun ZHANG ¹
Author Information

1. School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China
2. School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China
Publication Type:Research Article
Keywords: 3D printing; fused deposition molding technology; semi-solid extrusion technology; equipment principle; pharmaceutical excipient
From: Acta Pharmaceutica Sinica 2023;57(9):2640-2655
CountryChina
Language:Chinese
Abstract: 3D printing is an additive manufacturing technology with the help of digital control. Since FDA approved the first 3D printing drug in 2015, its research enthusiasm in the pharmaceutical field has been increasing year by year. In printing technology, fused deposition molding (FDM) and semi-solid extrusion (SSE) are the two most widely used extrusion molding technologies. In this review, recent advances of pharmaceutical 3D printing extrusion molding technology are reviewed from six aspects: mechanism, equipment, pharmaceutical excipients, applications, design and industrialization prospects of extrusion molding technology.