Clinical Features and CT Imaging Findings of Melioidosis Pneumonia
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.2023.0619
- VernacularTitle:类鼻疽肺炎的临床特征与CT影像学表现
- Author:
Sheng-shi MAI
1
;
Hong-zhang ZHU
2
;
Guang-qiang ZHAO
3
;
Hai CHEN
4
;
Meng ZHANG
1
Author Information
1. Department of Radiology， Sanya people’s hospital， Sanya 572000， China
2. Department of Radiology， The First Affiliated Hospital， Sun Yat-sen University， Guangzhou 510080， China
3. Department of Respiratory medicine， Sanya people’s hospital， Sanya 572000， China
4. Department of Clinical Laboratory， Sanya people’s hospital， Sanya 572000， China
- Publication Type:Journal Article
- Keywords:
melioidosis;
pneumonia;
burkholderia pseudomallei;
fever;
tomography;
X-ray computer
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2023;44(6):1038-1045
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo summarize and analyze the clinical features and CT imaging findings of melioidosis pneumonia in order to increase awareness of this disease. MethodsA retrospective study was done on clinical and CT imaging data of 68 cases with melioidosis pneumonia diagnosed from January 1， 2012 to April 1， 2023. ResultsOf the 68 cases， 62 presented with acute infection and 6 chronic infection， 88.2% were male， 85.3% were native residents of Hainan， 85.3% were farmers， 77.9% had onset in summer and autumn， 66.2% had diabetes， 100% had fever as the first clinical symptom， and 88.2% were confirmed positive by blood culture. In most patients， white blood cell count， neutrophil ratio， C-reactive protein and calcitonin levels increased， while lymphocyte ratio decreased， but no statistical difference was found between acute and chronic infection groups （P > 0.05）. Of the patients， 36.8% recovered， 42.6% got better， 11.8% patients became therapy-resistant and 8.8% died. CT image showed pathomorphological changes including nodules/masses， patchy ground-glass attenuation or large patchy consolidation or all of these at the same time. Acute and chronic infection groups had significant difference in pathomorphological changes （P = 0.01）， but no statistical difference in other imaging findings. Moreover， 36.8% of the patients developed extrapulmonary infections， 8.8% of which multi-site abscess formation. ConclusionsMelioidosis Pneumonia should be considered if the patient is the sojourner from epidemic area， or has diabetes， high fever and rapid-developing disease， with additional presence of multiple inflammatory lesions in lung CT.
