Research Progress on the Influence of Bile Acids on the Immune Response of Hepatitis B Vaccine
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.2023.0603
- VernacularTitle:胆汁酸影响乙肝疫苗免疫应答的研究进展
- Author:
Li-yan ZHU
1
;
Dan-dan HU
1
Author Information
1. Guangzhou Women and Children's Medical Center， Guangzhou Medical University， Guangzhou 510623， China
- Publication Type:Review
- Keywords:
bile acids;
hepatitis B vaccine;
immune response;
T-lymphocyte;
interferon;
terleukin
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2023;44(6):910-914
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis B vaccine （HepB） vaccination is the safest and most effective means of preventing hepatitis B virus （HBV） infection. HepB non-response is influenced by multiple factors， and solving the problem of poor immune response after HepB vaccination is of great significance for controlling HBV infection. Bile acids play an important role in human immune regulation， and whether bile acids have an effect on the HepB immune response has not been definitively studied. This article reviews the correlation between bile acids and HepB immune response， and provides a reference for further clarifying the pathogenesis and immunoprevention of bile acids in vaccine immunity.
