Orally Disintegrating Film: A Review of Its Formulation and Manufacturing Method
https://doi.org/10.47836/mjmhs.19.6.39
- Author:
Kai Bin Liew
1
;
Ganesan Gobal
1
;
Hanifah Mohd Rofiq
1
;
Hiu Ching Phang
1
;
Siew-Keah Lee
2
;
Long Chiau Ming
3
;
A.B.M. Helal Uddin
4
;
Yik Ling Chew
5
;
Vijayakumar Lakshminarayanan
6
Author Information
1. Faculty of Pharmacy, University of Cyberjaya, Persiaran Bestari, 63000 Cyberjaya, Selangor, Malaysia
2. M. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Jalan Sungai Long, Bandar Sungai Long, 43000, Kajang, Selangor, Malaysia
3. School of Medical and Life Sciences, Sunway University, Sunway City, 47500 Malaysia
4. Faculty of Pharmacy, International Islamic University Malaysia, Bandar Indera Mahkota, Kuantan, Pahang, Malaysia
5. Faculty of Pharmaceutical Sciences, UCSI University, Jalan Menara Gading, UCSI Heights, 56000 Cheras, Kuala Lumpur, Malaysia
6. Department of Pharmaceutical Technology, Hindusthan Institute of Technology, Coimbatore, Tamilnadu - 641032, India
- Publication Type:Review
- Keywords:
Orally disintegrating film, Solvent casting, Hot melt extrusion, Compliance, Polymer
- From:Malaysian Journal of Medicine and Health Sciences
2023;19(No.6):297-303
- CountryMalaysia
- Language:English
-
Abstract:
Oral route drug delivery system is still considered as the most convenient and patient friendly drug delivery route.
Over the decades, many research has been performed to improve the functionality oral dosage form. Orally disintegrating film (ODF) is a newer oral drug delivery system, which is in the form of a thin film that will disintegrate in
the oral cavity within a matter of seconds. The aim of this review paper is to recap ODF, its benefits, formulation
contents and manufacturing method. With more research and development work has been conducted on ODF, the
dosage form is expected to be manufactured and scaled up to be commercializable products to be sold in the market.
- Full text:11.2023my1693.pdf