Neuro-Behcet's Disease: Initial and Follow-up MR Imaging Findings.
10.3348/jkrs.1998.39.3.469
- Author:
Chan Sung KIM
1
;
Sun Seob CHOI
;
Ha Jong LEE
;
Dong Ho HA
;
Yong Il LEE
Author Information
1. Department of Diagnostic Radiology, College of Medicine, Dong-A University.
- Publication Type:Original Article
- Keywords:
Brain, MR;
Behcet's disease;
Magnetic resonance image (MR), contrast enhancement
- MeSH:
Brain Stem;
Follow-Up Studies*;
Humans;
Internal Capsule;
Magnetic Resonance Imaging*;
Retrospective Studies
- From:Journal of the Korean Radiological Society
1998;39(3):469-474
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study was to evaluate initial and follow-up MR imaging(MRI) findings ofneuro-Behcet's disease. MATERIALS AND METHODS: MRI of seven clinically diagnosed cases of neuro-Behcet's diseasewere retrospectively analysed in terms of involved site, pattern, signal intensity, contrast enhancement patternand changes seen on follow-up. Using a 0.35T or 1.0T unit T2- and T1-weighted spin-echo contrast-enhanced imageswere obtained in six patients. Follow-up MRI after steroid therapy lastion between two weeks and 16 months wasperformed in six patients. RESULTS: Lesions involved the midbrain(6/7), pons(5/7), thalamus(4/7), medullaoblongata(3/7), tegmentum(3/7), internal capsule(3/7), middle cerebellar peduncle(2/7), dentate nucleus(1/7),basal ganglia(1/7) and temporal lobe(1/7). They were 1-3cm in size, and their shape was ill-defined and patchy.Inhomogeneous high and low signal-intensity was seen on T2-weighted and T1-weighted images, respectively. In twoof six cases there was focal mild patchy enhancement. Euring follow-up lasting for between two weeks and 16 monthsafter steroid therapy, the lesions decreased in extent(n=5) or disappeared(n=1), and in the brainstem, focal brainatrophy occurred in three cases. CONCLUSION: Although MRI findings of neuro-Behcet's disease are nonspecific,common involvement of the brainstem, tegmentum and internal capsule, as well as improvement on follow-up MRI, maybe helpful diagnostic indicators of this condition.
