Treatment of Benign Cold Thyroid Nodule: Efficacy and Safety of US-guided Percutaneous Ethanol Injection.
10.3348/jkrs.1998.39.3.479
- Author:
Jeong Kon KIM
1
;
Ho Kyu LEE
;
Il Min AHN
;
Myung Joon LEE
;
Choong Gon CHOI
;
Dae Chul SUH
Author Information
1. Department of Diagnostic Radiology, Asan Medical Center University of Ulsan.
- Publication Type:Original Article
- Keywords:
Thyroid, US;
Thyroid, Neoplasms;
Alcohol
- MeSH:
Acute Pain;
Ethanol*;
Follow-Up Studies;
Humans;
Hyperplasia;
Proliferating Cell Nuclear Antigen;
Thyroid Gland*;
Thyroid Nodule*;
Ultrasonography;
Vocal Cord Paralysis
- From:Journal of the Korean Radiological Society
1998;39(3):479-483
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study was to evaluate the efficacy and safety of Us-guided percutaneous ethanolinjection for the treatment of benign cold thyroid nodules. MATERIALS AND METHODS: Twenty-five patients withbenign cold thyroid nodules (volume of each at least 2ml proven by PCNA to be adenomatous hyperplasia, and coldnodule by thyroid scan) underwent a total of one to three percutaneous ethanol injections (PEI) at intervals ofone or two months. The mean amount of ethanol used was 6.2(range, 1.5-8)ml, depending on the volume of the nodule. Follow up ultrasonography was performed one to four months after the final session. RESULTS: The initial volumeof nodules was 11.4+/-4.1(range, 2.5-41.4)ml, and in all cases this fell by 56.1+/-22.3%(range, 10.9-92.1%);in allcases, follow-up ultrasonography showed that echogeneity was lower and its pattern was heterogeneous. Trere wereno important longstanding complications; the most common side effect was acute pain at the injection site(n=9),and in one case, transient vocal cord palsy occurred. CONCLUSION: our results show that US-guided percutaneousinjection of ethanol is an effective and a safe procedure for the treatment of benign cold thyroid nodules, and isthus an alternative to surgery of hormone therapy.
