The physiological and pathological role of amyloid protein in the liver
10.3969/j.issn.1001-5256.2023.11.031
- VernacularTitle:淀粉样蛋白在肝脏中的生理病理作用
- Author:
Yekai ZONG
1
;
Jiangkai LIU
2
Author Information
1. Department of Hepatology and Spleen-Stomach， The First Clinical Medical College of Henan University of Chinese Medicine， Zhengzhou 450008， China
2. Department of Hepatology and Spleen-Stomach， The First Affiliated Hospital of Henan University of Chinese Medicine， Zhengzhou 450008， China
- Publication Type:Review
- Keywords:
Amyloid;
Amyloidosis;
Liver Diseases;
Pathologic Processes
- From:
Journal of Clinical Hepatology
2023;39(11):2730-2737
- CountryChina
- Language:Chinese
-
Abstract:
Amyloid protein （AP） is used to describe the fibrous aggregates that form when proteins are misfolded， and it is associated with a series of amyloidosis diseases. When AP is deposited in the liver， it will lead to liver amyloidosis， thereby inducing related pathological changes that affect the normal physiological function of the liver； however， this disease is rarely reported and often neglected in clinical practice. This article reviews the physiological and pathological effects and mechanisms of AP in the liver， so as to improve the understanding of AP-related diseases and provide a reference for related research and clinical treatment.
