Neoadjuvant therapy for hepatocellular carcinoma： Current situation and prospects
10.3969/j.issn.1001-5256.2023.11.027
- VernacularTitle:肝细胞癌新辅助治疗的现状与展望
- Author:
Zhisong NI
1
;
Junhan WEN
2
;
Weiwei ZHAO
3
;
Shoujun YU
4
;
Liang HAO
4
;
Yu CHENG
4
;
Xin LIU
5
Author Information
1. Department of State Capital，Yantai Affiliated Hospital of Binzhou Medical College， Yantai， Shandong 264001， China
2. The First Clinical Medical College of Shandong University of Traditional Chinese Medicine， Jinan 250011， China
3. Department of Traditional Chinese Medicine，Yantai Affiliated Hospital of Binzhou Medical College， Yantai， Shandong 264001， China
4. Minimally Invasive Center for Hepatobiliary， Pancreatic and Splenic Surgery， Yantai Affiliated Hospital of Binzhou Medical College， Yantai， Shandong 264001， China
5. First Department of Oncology， Yantai Hospital of Traditional Chinese Medicine， Yantai， Shandong 264001， China
- Publication Type:Review
- Keywords:
Carcinoma， Hepatocellular;
Neoadjuvant Therapy;
Treatment Outcome
- From:
Journal of Clinical Hepatology
2023;39(11):2697-2704
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma （HCC） is a major cause of cancer-related death， and surgical resection remains an important method for radical treatment， but it is urgently needed to solve the problem of high postoperative recurrence rate. Neoadjuvant therapy can reduce the high recurrence rate after surgery， and there are little benefits from neoadjuvant therapy for HCC due to a lack of effective treatment methods in the past. At present， combination therapy based on immune checkpoint inhibitors has a relatively high response rate and has thus changed the treatment landscape for patients with advanced HCC. This urges investigators to reexamine the neoadjuvant treatment strategies for HCC， and it is expected that neoadjuvant therapy can provide new opportunities， reduce the postoperative recurrence rate， and improve the survival rate after treatment. This article discusses the current status and prospects of neoadjuvant therapy for HCC and related hot topics， so as to provide more ideas for exploring neoadjuvant therapy for HCC.
