Ovarian Stromal Tumors: A rare cause of postmenopausal virilization

Author: May Uyking-Naranjo ¹ ; Roberto Mirasol ¹
Author Information

1. Section of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine St. Lukes Medical Center, Quezon City, Philippines
Publication Type:Journal Article
Keywords: Postmenopausal virilization; Ovarian tumors
MeSH: Hyperandrogenism
From: Journal of the ASEAN Federation of Endocrine Societies 2013;28(1):78-82
CountryPhilippines
Language:English
Abstract: We report the case of a 61-year-old Filipino woman with postmenopausal virilization presenting with androgenic alopecia, progressive hirsutism and deepening voice over 5 years due to elevated testosterone levels. Ultrasound and computed tomography imaging suggested a left adnexal mass. Histology obtained following total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAHBSO) demonstrated stromal luteoma of the left ovary. On immunohistochemistry, the tumor was positive for inhibin. Postoperatively, there was note of rapid normalization of testosterone level.
Full text:56-Article Text-281-1-10-20140524.pdf