Association of 25(OH)D serum concentrations on health-related quality of life among patients with low Vitamin D
- Author:
Odessa Tolentino-Wilson
1
;
Carolyn Narvacan-Montano
1
Author Information
- Publication Type:Journal Article
- Keywords: 25(OH)D
- MeSH: Vitamin D; Quality of Life
- From: Journal of the ASEAN Federation of Endocrine Societies 2014;29(1):54-58
- CountryPhilippines
- Language:English
-
Abstract:
Objective:To determine the association between 25-hydroxyvitamin D [25(OH)D] serum concentrations and health-related quality of life (HRQoL) among patients with low vitamin D levels.
Methodology:This prospective cohort study included 76 patients (ages 18 to 59; 54 females and 22 males) who had baseline 25(OH)D below 30 ng/ml and were prescribed a Vitamin D supplement for eight weeks. HRQoL was assessed at baseline and after 8 weeks through the Functional Assessment of Non-Life Threatening Conditions (FANLTC) questionnaire.
Results:HRQoL of the participants who were Vitamin D deficient and insufficient at baseline were basically the same (p-values >0.05). After supplementation, the personal well-being and overall HRQoL of the participants who were Vitamin D sufficient were significantly higher than those who were Vitamin D deficient or insufficient (p-values < 0.05). Moreover, after supplementation, all the HRQoL subscale scores as well as the total HRQoL scores of the participants were significantly higher than their baseline HRQoL scores (p-values < 0.05).
Conclusion:The improved HRQoL scores after Vitamin D supplementation showed that there is a significant association between 25(OH)D serum concentrations and HRQoL. - Full text:116-Article Text-565-1-10-20140531.pdf