Primary hyperparathyroidism from parathyroid carcinoma presenting with multiple skeletal fractures and brown cell tumors
- Author:
Christian Cesar Esplana
1
;
Jerome Rebollos Barrera
1
Author Information
- Publication Type:Case Reports
- MeSH: Hypercalcemia; Hyperparathyroidism; Parathyroid Neoplasms
- From: Journal of the ASEAN Federation of Endocrine Societies 2015;30(2):178-183
- CountryPhilippines
- Language:English
- Abstract: We report the case of a 19-year old Filipino woman who presented with hard masses on the left upper arm and leg with multiple fractures on all extremities. Her serum calcium and intact parathyroid hormone (iPTH) levels were elevated, while serum phosphorus was low. Ultrasonography of the neck revealed a left inferior parathyroid mass. Ultrasound-guided fine needle aspiration of the mass revealed findings consistent with parathyroid carcinoma. After hydration and administration of diuretic and bisphosphonate to control the severe hypercalcemia, she subsequently underwent 3½ gland parathyroidectomy with en-bloc left thyroid lobectomy. There was immediate normalization of biochemical indices after surgery. Three months later, the fractures on all extremities were fully resolved.
- Full text:251-Article Text-2885-2-10-20151215.pdf
