Effect of Two Different Meal Compositions on 1-hour Plasma Ghrelin Levels in Young Men
https://doi.org/10.47836/mjmhs.19.5.26
- Author:
Brinnell Annette Caszo
1
;
Sangeetha Shyam
2
;
Purushotham Krishnappa
1
;
Justin Vijay Gnanou
1
Author Information
1. School of Medicine, International Medical University, 57000 Kuala Lumpur, Malaysia
2. School of Health Sciences, International Medical University, 57000 Kuala Lumpur, Malaysia
- Publication Type:Journal Article
- Keywords:
Appetite, Hunger, Satiety, Diet composition, Visual analogue scale
- From:Malaysian Journal of Medicine and Health Sciences
2023;19(No.5):185-189
- CountryMalaysia
- Language:English
-
Abstract:
Introduction: Calorie restriction is the main strategy for loosing body weight in obese individuals. However, persistence to this strategy is a major challenge. Ghrelin, a hormone that influences an individual to consume food by
modulating the feelings of hunger. This effect may be influenced by the % fat composition of a meal. Materials and
Methods: Twelve young male participants with normal BMI, were administered in random order one of 2 isocaloric
meals after an overnight fast. The 2 meals contained either 31 or 52% fat. After a 7 day gap, cross-over of the participants was carried out and they consumed the other meal similarly. Ghrelin levels were measured after fasting and
1 hour after diet consumption. An appetite rating on a visual analogue scale (VAS) was used to measure perceived
hunger and satiety before and after the meal. Results: When compared to the baseline values, an average of 34% and
20% decrease in ghrelin levels were noted after the high-fat meal (p<0.025), and low-fat meal respectively. Analysis
of the VAS showed that feelings of hunger decreased, while feelings of satiety increased after the meal, however there
was no difference between the two meals. Conclusion: Thus, within this study group, though the feelings of hunger
and satiety was comparable, consumption of isocaloric high fat caused ghrelin levels to decrease within one hour
post meal. This shows that manipulation of % fat of the diet can achieve lower post-meal ghrelin levels.
- Full text:11.2023my1628.pdf
