Further discussion on the antiviral treatment of chronic hepatitis B patients with indeterminate phase
10.3969/j.issn.1001-5256.2023.10.001
- VernacularTitle:不确定期慢性乙型肝炎抗病毒治疗再探讨
- Author:
Hui ZHUANG
1
Author Information
1. Department of Microbiology and Center of Infectious Diseases, Peking University Health Science Center, Beijing 100191, China
- Publication Type:Journal Article
- Keywords:
Hepatitis B Virus;
Hepatitis B, Chronic;
Indeterminate Phase;
Carcinoma, Hepatocellular;
Therapeutics
- From:
Journal of Clinical Hepatology
2023;39(10):2273-2276
- CountryChina
- Language:Chinese
-
Abstract:
This paper discusses further on the antiviral treatment of chronic hepatitis B patients with indeterminate phase. These patients have a high proportion of significant necroinflammation and fibrosis in the liver, and a higher risk of disease progression compared with those with true HBeAg-positive chronic hepatitis B virus (HBV) infection (formerly called the immune tolerance phase) or HBeAg-negative chronic HBV infection (formerly called the immune control phase). Antiviral therapy may reduce the risk of HBV-related hepatocellular carcinoma in chronic hepatitis B patients with indeterminate phase.