Effect of Paint Exposure Among Paint Workers and DNA Damage: A Scoping Review
https://doi.org/10.47836/mjmhs.19.4.47
- Author:
Afiqah Saironi
1
;
Normah Awang
1
;
Anuar Ithnin
2
;
Nurul Farahana Kamaluddin
1
;
Farah Wahida Ibrahim
1
;
Kok Meng Chan
1
Author Information
1. Centre for Toxicology and Health Risk Research (CORE), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia
2. Centre of Community and Health Studies (ReaCH), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia
- Publication Type:Review
- Keywords:
Paint exposure, Organic solvent exposure, Paint workers, DNA damage, Oxidative stress
- From:Malaysian Journal of Medicine and Health Sciences
2023;19(No.4):342-353
- CountryMalaysia
- Language:English
-
Abstract:
Paint contains various complex chemical mixtures, such as aliphatic hydrocarbons, aromatic hydrocarbons (primarily toluene), ketones, and benzene as reported at previous studies. Toxicity from some chemicals can cause early
DNA damage with various factors. A scoping review was conducted via literature review on relevant studies on the
effect of paint exposure on paint workers and DNA damage. A systematic search was conducted in October 2021
via PubMed, Scopus, and Web of Science databases. The key terms used were paint, solvent-based paint, organic
solvent, mixed organic solvent, occupational exposure and DNA damage, oxidative stress, genotoxicity on a painter,
paint worker. From 561 articles, only 13 articles were finally selected based on the inclusion, exclusion criteria, and
eligibility criteria. The literature showed that biomonitoring studies on painters were consistently reporting positive
and significant DNA damage due to exposure to different types of compounds mixed in a paint. However, there were
fewer studies on paint manufacturing factory workers compared to painters while paint manufacturing workers exposed various chemical everyday during the paint production which potentially susceptible to occupational toxicity.
In conclusion, this review suggests that exposure to paints could induce early DNA damage among paint workers
and further investigations on paint exposure among paint manufacturing factory workers and the DNA damage were
needed in order to improve occupational health among paint workers in the future.
- Full text:11.2023my1598.pdf
