Metastatic mammary carcinoma in a mature singleton placenta
- Author:
Francia Victoria A . de los Reyes
1
Author Information
1. Pathology Laboratory
- Publication Type:Journal Article
- Keywords:
Placental metastasis;
Metastatic breast carcinoma;
Pregnancy-associated breast carcinoma
- MeSH:
Immunohistochemistry
- From:
Health Sciences Journal
2017;6(1):38-44
- CountryPhilippines
- Language:English
-
Abstract:
Introduction:Placental metastasis from maternal malignancies is a rare occurrence with a
significantly adverse prognosis on the mother with no known effect or established risk factors for the
newborn. As such, characterization of these lesions is necessary to serve as a stepping stone for
more exhaustive studies regarding this presentation.
Case Summary :This is a case of a metastatic breast carcinoma in a mature singleton placenta in
a 39 year old woman diagnosed with invasive breast carcinoma of no special type/invasive ductal
carcinoma, not otherwise specified, during the second trimester of pregnancy. Also discussed are the
immunohistochemistry studies done to confirm the origin of the tumor. A comparison of the ER, PR,
and HER2/neu receptor status between the primary lesion and the placental metastasis was also
done.
Conclusion :Pregnancy-associated breast cancer is a lesion that carries adverse prognosis for the
mother because of the delay in diagnosis attributable to confusion of symptomatology. The pertinent
problem in pregnancy-associated breast cancer with placental metastasis is the deficiency of the
placenta to induce tumor metastasis away from itself.
- Full text:UERMMMCI 21.pdf
