Factors Associated with Presence of Human Papillomavirus  Infection among Women: Findings from New Cervical Cancer  Screening in Kelantan, Malaysia

Nur Dalilah Mohd Zin; Tengku Alina Tengku Ismail; Noran Hashim

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Factors Associated with Presence of Human Papillomavirus Infection among Women: Findings from New Cervical Cancer Screening in Kelantan, Malaysia

Author: Nur Dalilah Mohd Zin ¹ ; Tengku Alina Tengku Ismail ¹ ; Noran Hashim ²
Author Information

1. Department of Community Medicine, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
2. Family Health Unit, Kelantan State Health Department, Ministry of Health Malaysia, Level 5, Wisma Persekutuan, Jalan Bayam, 15590, Kota Bharu, Kelantan, Malaysia
Publication Type:Journal Article
Keywords: Factor associated, Human papillomavirus (HPV), HPV DNA test, HPV screening, Cervical cancer screening
From:Malaysian Journal of Medicine and Health Sciences 2023;19(No.4):84-92
CountryMalaysia
Language:English
Abstract: Introduction: Human papillomavirus (HPV) infection is known to cause cervical cancer worldwide. Recently, Malaysia introduced HPV DNA detection testing for cervical cancer screening program. However, knowledge regarding factors for HPV infection among women still limited. Thus, this study aimed to determine the prevalence and factors associated with HPV infection among women in Kelantan, a north-eastern state of Malaysia. Methods: This study used secondary data extracted from HPV DNA test registry book and HPV DNA laboratory request forms. Data on all Malaysian women aged 30 to 49 years old in 2019 reported in registry book were included. Simple random sampling was applied. All information from book and forms were collected using proforma and analysed using SPSS. The outcomes were categorised into HPV infection and non-HPV infection. The parameters related to factors associated with HPV infection were determined using multivariable logistic analysis. Results: The prevalence of HPV infection among women attending the new cervical screening was 8.4% (95% CI 6.4%, 10.3%). Those aged between 30 and 39 years old (AdjOR 2.09; 95% CI 1.16, 3.78, p=0.014), had 5 or more parities (AdjOR 2.82; 95% CI 1.58, 5.06, p<0.001) and hormonal contraception users (AdjOR 7.48; 95% CI 4.07, 13.76, p<0.001) were significantly associated with HPV infection. Conclusion: Overall, the prevalence of HPV infection from this study is comparable to the local and international studies. Age, number of parities and hormonal contraception users influence the HPV infection. This finding could help in designing more targeted screening for cervical cancer.
Full text:11.2023my1565.pdf