Imaging Characteristics of Brain SPECT, PET, and MRI in Neurosyphilis
10.1007/s13139-021-00684-9
- Author:
Eun Kyoung CHOI
1
;
Young Do KIM
;
Hyeonseok JEONG
;
Yong-An CHUNG
;
Jin Kyoung OH
;
In-Uk SONG
Author Information
1. Department of Nuclear Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea
- Publication Type:CASE REPORT
- From:Nuclear Medicine and Molecular Imaging
2021;55(1):48-51
- CountryRepublic of Korea
- Language:English
-
Abstract:
The incidence of neurosyphilis has declined since effective penicillin therapy against Treponema pallidum was introduced. However, the diagnosis of neurosyphilis early in the disease course is very important in order to select appropriate antibiotic therapy. We report brain MRI, SPECT with Tc-99m ECD, and PET with F-18 FDG findings before antibiotic therapy in a neurosyphilis patient with neurological symptoms. The cerebral cortices showed hypoperfusion with a patchy distribution on SPECT and foci with high signal intensity on MRI, suggesting ischemia. Brain PET showed areas with hypometabolism in the temporoparietal lobes bilaterally.
