Assignments of the tyrosinase related protein-1 and -2 genes to human chromosome bands 9p23 and 13q32.1 by in situ hybridization.
10.3349/ymj.2000.41.3.398
- Author:
Young Mi LEE
1
;
Mahn Joon HA
;
Min Sook RYU
;
Eunpyo MOON
;
Sungbin IM
;
Hyon Ju KIM
;
Wankee KIM
Author Information
1. Institute for Medical Sciences, College of Natural Sciences, Ajou University, Suwon, Korea. wkim@ madang.ajou.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Tyrosine related proteins;
bacterial artificial chromosome library;
fluorescence in situ hybridization
- MeSH:
Chromosomes, Human, Pair 13/genetics*;
Chromosomes, Human, Pair 9/genetics*;
Gene Library;
Human;
In Situ Hybridization, Fluorescence;
Intramolecular Oxidoreductases/genetics*;
Proteins/genetics*
- From:Yonsei Medical Journal
2000;41(3):398-400
- CountryRepublic of Korea
- Language:English
-
Abstract:
To determine the precise chromosomal localization of tyrosine related protein-1 and -2 (TRP-1 and TRP-2) genes by fluorescence in situ hybridization, we used DNAs isolated from human bacterial artificial chromosome clones. They contain genomic sequences with approximately 120 kb inserts for TRP-1 and TRP-2. The TRP-1 and TRP-2 genes were assigned to human chromosome bands 9p23 and 13q32.1, respectively. These results confirmed the previously mapped location for the TRP-1 gene and more precisely located the TRP-2 gene, which had previously been mapped to chromosome 13q31-q32.
