Factors Associated with Dose Determination of Radioactive Iodine Therapy for Differentiated Thyroid Cancer
10.1007/s13139-018-0522-0
- Author:
Chae Moon HONG
1
;
Byeong Cheol AHN
Author Information
1. Department of Nuclear Medicine, School of Medicine, Kyungpook National University, 680, Gukchaebosang-ro, Jung-gu, Daegu 41944, Republic of Korea. abc2000@knu.ac.kr
- Publication Type:Review
- From:Korean Journal of Nuclear Medicine
2018;52(4):247-253
- CountryRepublic of Korea
- Language:English
-
Abstract:
Radioactive iodine (RAI) therapy for differentiated thyroid cancer has been successfully used for more than 70 years. However, there is still plenty of controversy surrounding the use and doses of radioiodine. There is insufficient evidence to answer the questions. Recent American Thyroid Association (ATA) guidelines seem to favor low-dose RAI, based on recent clinical trials and meta-analyses. However, long-term follow-up data remains limited, and there are additional factors we should consider that might affect the efficacy of RAI therapy. Therefore, until sufficient data are available, it is necessary to remain cautious about determining RAI doses by considering multiple patient-specific variables.
