A case of membranoproliferative glomerulonephritis associated with a hydatidiform mole.
10.3349/ymj.2000.41.3.407
- Author:
Byoung Geun HAN
1
;
Mi Hye KIM
;
Eung Ho KARL
;
Sun Won HONG
;
Seung Ok CHOI
Author Information
1. Department of Nephrology, Yonsei University Wonju College of Medicine, Wonju, Korea. neptune@wonju.yonsei.ac.kr
- Publication Type:Case Report ; Review
- Keywords:
Glomerulonephritis;
hydatidiform mole
- MeSH:
Case Report;
Diagnosis, Differential;
Edema/etiology;
Female;
Glomerulonephritis, Membranoproliferative/pathology;
Glomerulonephritis, Membranoproliferative/etiology*;
Hematuria/etiology;
Human;
Hydatidiform Mole/therapy;
Hydatidiform Mole/diagnosis*;
Hydatidiform Mole/complications*;
Middle Age;
Pregnancy;
Proteinuria/etiology;
Uterine Neoplasms/therapy;
Uterine Neoplasms/diagnosis*;
Uterine Neoplasms/complications*
- From:Yonsei Medical Journal
2000;41(3):407-410
- CountryRepublic of Korea
- Language:English
-
Abstract:
We treated a 54-year-old woman who was suffering from membranoproliferative glomerulonephritis associated with a complete type of hydatidiform mole. The renal manifestations were proteinuria and hematuria. A renal biopsy, performed before gynecologic management, disclosed focal and segmental subendothelial deposits with a proliferation of the mesangial cell and showed irregularly thickened capillary loops by light and electronmicroscoy. Genralized edema, proteinuria and hematuria were completely recovered by suction and curettage of the hydatidiform mole with prophylactic chemotherapy. The clinical manifestation of earlier presented 3 cases have been the nephrotic syndrome. The common feature of them was a complete remission of the nephropathy after the removal of the hydatidiform mole. The relationship between the hydatidiform mole and glomerulonephritis remains unresolved at present. But we concluded that the hydatidiform mole might be a cause of glomerulonephritis in this case.
