Hot Embolus Artifact Mimicking Disease Progression in Post‑therapy177Lu‑DOTATATE Scan: Incremental Value of SPECT/CT
10.1007/s13139-023-00789-3
- Author:
Piyush AGGARWAL
1
;
Anupriya ANWARIYA
;
Anwin Joseph KAVANAL
;
Ashwani SOOD
;
Santosh Ranjan JENA
;
Bhagwant Rai MITTAL
Author Information
1. Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
- Publication Type:CASE REPORT
- From:Nuclear Medicine and Molecular Imaging
2023;57(3):159-161
- CountryRepublic of Korea
- Language:English
-
Abstract:
Peptide receptor radionuclide therapy (PRRT) has become an established treatment for patients with inoperable and/or metastatic, well-differentiated neuroendocrine tumors with overexpression of somatostatin receptor type 2 (SSTR-2). The post-therapy 177Lu-DOTATATE whole-body scan not only assesses the biodistribution of the lesions seen on pre-therapy68 Ga-SSTR PET/CT scan but also provides a quick assessment of disease status and dosimetry during treatment. Like any other radionuclide scan, the whole-body 177Lu-DOTATATE scan may also show abnormal radiotracer uptake, which may require further imaging to establish its exact etiology. Though radiotracer emboli mimicking focal pulmonary lesions have been described with 18F-FDG and 68 Ga-DOTANOC PET/CT scans, similar artifacts with post-therapy 177Lu-DOTATATE scans have not been described. Herein, we report two cases of hot emboli in the post-therapy 177Lu-DOTATATE scans.
