Islet cell hyperplasia of the pancreas presenting as hyperinsulinemic hypoglycemia in an adult.
10.3349/ymj.2000.41.3.426
- Author:
Youn Wha KIM
1
;
Yong Koo PARK
;
Jae Hoon PARK
;
Sang Mok LEE
;
Juhie LEE
;
Suk Whan KO
;
Moon Ho YANG
Author Information
1. Department of Pathology, College of Medicine, Kyung Hee University, Seoul, Korea. kimyw@nms.kyunghee.ac.kr
- Publication Type:Case Report
- Keywords:
Islet cell hyperplasia;
hyperinsulinemic hypoglycemia;
pancreas;
adult
- MeSH:
Aged;
Case Report;
Human;
Hyperinsulinemia/etiology*;
Hyperplasia;
Hypoglycemia/etiology*;
Islets of Langerhans/surgery;
Islets of Langerhans/pathology*;
Male;
Pancreatectomy/methods;
Treatment Outcome
- From:Yonsei Medical Journal
2000;41(3):426-429
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 72-year-old man who had suffered several episodes of syncope was diagnosed as having hyperinsulinemic hypoglycemia. Although imaging studies and percutaneous transhepatic portal venous sampling did not reveal the existence of any tumors in the pancreas, distal pancreatectomy was performed because the possibility of a small pancreatic endocrine tumor could not be completely rejected. External examination of the surgically removed pancreas did not reveal any tumors. Microscopically, the pancreas exhibited diffuse islet cell hyperplasia without nesidioblastosis. The patient remains euglycemic and has tolerated 24-hour fasting without any medication for a period of 10 months after the operation.
