Discussion on the Formation and Prevention Strategies of Chemotherapy Resistance of Malignant Tumor Based on “Yin Fire” Theory
10.13288/j.11-2166/r.2023.20.007
- VernacularTitle:从“阴火”理论探讨恶性肿瘤化疗耐药的形成及防治策略
- Author:
Xinyan WANG
1
;
Tong ZHOU
1
;
Jinglei LI
2
;
Wei HOU
2
Author Information
1. Graduate School of Beijing University of Chinese Medicine， Beijing 100029
2. Guang'anmen Hospital， China Academy of Chinese Medical Sciences
- Publication Type:Journal Article
- Keywords:
malignant tumor;
chemotherapy resistance;
Yin Fire;
tonifying the middle;
elevating yang;
dissipating fire
- From:
Journal of Traditional Chinese Medicine
2023;64(20):2082-2085
- CountryChina
- Language:Chinese
-
Abstract:
Chemotherapy is currently the main clinical treatment method for malignant tumors， and chemotherapy resistance is the main factor leading to chemotherapy failure and malignant tumor recurrence and metastasis. The cha-racteristics of malignant tumors formation were regarded as similar to the “Yin Fire” theory， manifested that deficiency of original qi as the foundation of malignant tumors， imbalance of original qi and yin fire as the internal cause of malignant tumor progression， and the internal environment of phlegm-blood stasis-toxicity-deficiency caused by yin fire promoted the formation of chemoresistance. In the treatment of chemoresistance of malignant tumors， traditional Chinese medicine should focus on treating disease before its onset by tonifying the spleen and strengthening the middle， nou-rishing the original qi， and reinforcing healthy qi and anti-cancer； during the treatment， the clinicians should regulate the qi and detoxify to clear yin fire， and improve the internal environment. Summarily， the strategies were adjusting the balance of internal environment of original qi and yin fire， and conducting a comprehensive treatment during the whole process， to provide new ideas for the treatment of chemoresistance of malignant tumors with traditional Chinese medicine.
