The first imported case of visceral leishmaniasis in Shenzhen City.
10.16250/j.32.1374.2023105
- Author:
Y HUANG
1
;
S GAO
2
;
Y LI
2
Author Information
1. Nanshan District Center for Disease Control and Prevention, Shenzhen, Guangdong 518054, China.
2. Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong 518055, China.
- Publication Type:Journal Article
- Keywords:
Imported case;
Shenzhen City;
Visceral leishmaniasis
- MeSH:
Humans;
Fever;
High-Throughput Nucleotide Sequencing;
Leishmania donovani/genetics*;
Leishmaniasis, Visceral/drug therapy*
- From:
Chinese Journal of Schistosomiasis Control
2023;35(4):424-426
- CountryChina
- Language:Chinese
-
Abstract:
A patient with fever, chills, and pancytopenia as major clinical manifestations was presented. To investigate the cause, the patient's peripheral blood was collected for pathogen screening using metagenomic next - generation sequencing (mNGS). The DNA sequence of Leishmania donovani was detected, and Leishmania amastigotes were found in bone marrow smears using microscopy. The case was therefore definitively diagnosed as visceral leishmaniasis, and was cured and discharged from hospital following treatment with liposomal amphotericin B for 14 days. This is the first imported case of visceral leishmaniasis since the founding of Shenzhen City in 1979.
