Synchrotron Radiation Imaging of Breast Tissue Using a Phase-contrast Hard X-ray Microscope.
- Author:
Young Ju JEONG
1
;
Jin Gu BONG
;
Sung Hwan PARK
Author Information
1. Department of Surgery, College of Medicine, Catholic University of Daegu, Daegu, Korea. shwpark@cu.ac.kr
- Publication Type:Original Article
- Keywords:
Hard X-ray microscopic imaging;
Phase-contrast;
Synchrotron radiation;
Breast imaging
- MeSH:
Breast;
Breast Diseases;
Breast Neoplasms;
Humans;
Light;
Synchrotrons
- From:Korean Journal of Medical Physics
2011;22(3):117-123
- CountryRepublic of Korea
- Language:English
-
Abstract:
Synchrotron radiation (SR) imaging enables us to observe internal structures of biologic samples without staining. In this study, we obtained X-ray microscopic images of human breast tissues with 11.1 KeV hard X-ray microscope of the Pohang light source and used zone plates and phase-contrast technique to get high resolution X-ray images. Hard X-ray microscopic images of fibrocystic change and breast cancer tissues with a spatial resolution of 60 nm were obtained and from these images, we could observe the micro-structures of human breast tissue. Also we analyzed and compared these images, which revealed distinct features of each condition. In conclusion, SR imaging with phase-contrast hard X-ray microscope for medical application, especially in breast disease can give some useful information for clinical research.
