Research progress on the characteristics and rapid diagnostic tools of early lung adenocarcinoma subtypes
- VernacularTitle:早期肺腺癌亚型特征及快速诊断工具的研究进展
- Author:
Kui WANG
1
;
Hongyi ZHANG
2
;
Yao PANG
2
;
Zijiang ZHU
1
Author Information
1. 1. The First Clinical Medical College of Gansu University of Chinese Medicine (Gansu Provincial Hospital), Lanzhou, 730000, P. R. China 2. The Second Department of Thoracic Surgery, Gansu Provincial Hospital, Lanzhou, 730000, P. R. China
2. The Second Department of Thoracic Surgery, Gansu Provincial Hospital, Lanzhou, 730000, P. R. China
- Publication Type:Journal Article
- Keywords:
Lung adenocarcinoma subtypes;
micropapillary;
solid;
rapid diagnosis;
semi-dry dot-blot;
artificial intelligence;
mass spectrometry;
review
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2023;30(10):1507-1512
- CountryChina
- Language:Chinese
-
Abstract:
Lung adenocarcinoma has become the most common type of lung cancer. According to the 2015 World Health Organization histological classification of lung cancer, invasive lung adenocarcinoma can be divided into 5 subtypes: lepidic, acinar, papillary, solid, and micropapillary. Relevant studies have shown that the local lobectomy or sublobectomy is sufficient for early lepidic predominant adenocarcinoma, while lobectomy should be recommended for tumors containing micropapillary and solid ingredients (≥5%). Currently, the percentage of micropapillary and solid components diagnosed by frozen pathological examination is 65.7%, and the accuracy of diagnosis is limited. Therefore, to improve the accuracy of diagnosis, it is necessary to seek new methods and techniques. This paper summarized the characteristics and rapid diagnosis tools of early lung adenocarcinoma subtypes.
