Hepatic Changes Resembling the Indian Childhood Cirrhosis in an IgM anti-CMV Positive Infant.
- Author:
Soo Im CHOI
;
Chan Il PARK
;
Ki Sup CHUNG
- Publication Type:Original Article
- Keywords:
Cytomegalovirus;
Cirrhosis;
Indian childhood cirrhosis;
Mallory body
- MeSH:
Infant;
Child;
Male;
Female;
Infant, Newborn;
Humans
- From:Korean Journal of Pathology
1987;21(2):90-93
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This is to describe a neonatal hepatitis with pericellular hepatic fibrosis and Mallory bodies in a sero-positive infant for IgM anti-CMV. A necropsy of the liver revealed severe heaptocellular swelling with many intracytoplasmic hyaline bodies, pronounced fibrosis of a creeping type, bile stasis with ductular proliferation, and the lack of parenchymal regeneration. These microscopical changes of the liver resembled those of Indian Childhood Cirrhosis (ICC). In the present case the patient's serum IgM anti-CMV is the only clue for the etiological diagnosis.