Analysis of the clinicopathological characteristics of thymoma patients and the influencing factors for prognosis
- VernacularTitle:胸腺瘤患者的临床病理特征及预后影响因素分析
- Author:
Taiji XIE
1
;
Ling GUO
2
;
Ruoyan GONG
3
;
Qianlong TANG
4
;
Run XIANG
2
;
Wei DAI
2
;
Shaohua XIE
2
;
Ke ZHOU
3
;
Tianpeng XIE
2
;
Qiang LI
2
Author Information
1. 1. Department of Thoracic Surgery, Sichuan Cancer Hospital, Chengdu, 610041, P. R. China 2. Chengdu Medical College, Chengdu, 610500, P. R. China 3. Department of General Surgery, Muchuan County Peoples Hospital, Leshan, 614000, Sichuan, P. R. China
2. Department of Thoracic Surgery, Sichuan Cancer Hospital, Chengdu, 610041, P. R. China
3. School of Public Health, Chongqing Medical University, Chongqing, 400016, P. R. China
4. 1. Department of Thoracic Surgery, Sichuan Cancer Hospital, Chengdu, 610041, P. R. China 2. Chengdu Medical College, Chengdu, 610500, P. R. China
- Publication Type:Journal Article
- Keywords:
Thymoma;
treatment method;
survival time;
recurrence and metastasis;
influencing factors;
prognosis
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2023;30(10):1407-1414
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinicopathological characteristics of thymoma patients and the influencing factors for prognosis. Methods Thymoma patients who received treatment in Sichuan Cancer Hospital from March 2015 to March 2021 were collected. Clinical data of the patients were analyzed using Kaplan-Meier and Cox regression analyses. Results A total of 177 patients were included. There were 89 males and 88 females aged 17-88 (52.3±13.0) years, including 160 surgical patients and 17 non-surgical patients. There were 160 patients survived, 17 died of thymoma, and 5 had recurrence and metastasis. Overall, the 1-year, 3-year and 5-year progression-free survival rates were 94.4%, 88.7%, 88.1%, respectively; the 1-year, 3-year and 5-year overall survival rates were 94.9%, 91.5%, 91.0%, respectively. The Kaplan-Meier analysis showed that World Health Organization classification, clinical symptoms, Masaoka-Koga staging, treatment methods and surgery were statistically associated with progression-free survival; clinical symptoms, age, treatment methods and surgery were statistically associated with overall survival (P<0.05). Patients with younger age (P=0.018), without clinical symptoms (P=0.039), and with surgical treatment (P=0.004) had higher overall survival rates; those patients undergoing surgery had a higher progression-free survival rate (P=0.002). Conclusion Age, clinical symptoms and surgical treatment are independent factors influencing the prognosis of patients with thymoma.
