Effects of Chemically Interesterified Palm Olein on Lipid Profiles in Hamsters
https://doi.org/10.47836/mjmhs.19.2.45
- Author:
Che Anishas Che Idris
1
;
Teng Kim-Tiu
1
;
Siti Syairah Mohd Mutalip
2
;
John Kwong Siew Shia
2
Author Information
1. Nutrition Unit, Product Development and Advisory Services Division, Malaysian Palm Oil Board, 43000 Kajang, Selangor, Malaysia
2. Department of Pharmaceutical Life Sciences, Faculty of Pharmacy, Universiti Teknologi MARA Selangor, 42300 Bandar Puncak Alam, Selangor, Malaysia
- Publication Type:Other Types
- Keywords:
Fatty acid, Palmitic acid, Palm olein, Positional distribution, Stereospecific position
- From:Malaysian Journal of Medicine and Health Sciences
2023;19(No.2):329-333
- CountryMalaysia
- Language:English
-
Abstract:
Palm olein (POo) has been perceived as atherogenic due to its high proportion of palmitic acid (41.2%) content. It
is interesting that most of the palmitic acid of POo is located at stereospecific numbering sn-1 and sn-3 positions of
the triacylglycerol (TAG) backbone. The present study aims to investigate the effects of positional distribution of fatty
acids on the lipid profiles of POo or chemically interesterified palm olein (CIE POo) fed hamsters in comparison to
high oleic sunflower oil (HOSO) fed hamsters. Male weanling Syrian golden hamsters (n=10 for each group), were
fed diets formulated with the above oils for 12 weeks. There was no significant difference between CIE POo and
HOSO groups for total cholesterol (TC). CIE POo with increased amount of palmitic acid (43.2%) at sn-2 position
did not cause significant increases in TC levels compared to the HOSO group. In addition, the POo group has significantly higher high-density lipoprotein cholesterol (HDL-C) than that of the HOSO group, P = 0.011 (< 0.05) while
the HOSO group has significantly lower total cholesterol (TC) levels than that of the POo group, P = 0.012 (< 0.05).
- Full text:11.2023my1495.pdf
