Cardiobacterium hominis Endocarditis in a Healthy Adult - Rare but Not to Be Missed
https://doi.org/10.47836/mjmhs.19.1.48
- Author:
Lee Hwa Chu
1
,
2
;
Hasni Mahayidin
2
;
Rosni Ibrahim
2
Author Information
1. Department of Pathology, Hospital Kuala Lumpur, Jalan Pahang, 50586 Kuala Lumpur, Wilayah Persekutuan Kuala Lumpur&
2. Department of Medical Microbiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor
- Publication Type:Case Reports
- Keywords:
Cardiobacterium hominis, endocarditis, HACEK, polymerase chain reaction
- From:Malaysian Journal of Medicine and Health Sciences
2023;19(No.1):372-374
- CountryMalaysia
- Language:English
-
Abstract:
Cardiobacterium hominis is part of HACEK group and an atypical cause of infective endocarditis. It may cause similar clinical presentation to other cause of endocarditis. Establishing the diagnosis is challenging as it is a fastidious
organism which rarely affects individual without previous cardiac lesion and requires advanced diagnostic tools
for identification of species. A 23-year-old previously healthy man presented with intermittent fever for two months
associated with palpitations and lethargy. He had undergone a dental procedure four months before the presenting
symptoms. Physical examination revealed a pansystolic murmur best heard over the apex. Three aerobic blood culture bottles were positive and Gram stain consistently showed pleomorphic Gram-negative rods. The organism grew
as tiny pin-point opaque colonies on sheep blood agar and chocolate agar after 48 hours of incubation but no growth
was seen on MacConkey agar. Unsuccessful identification with VITEK 2 NH and VITEK 2 GN was later confirmed by
polymerase chain reaction as C. hominis. He was treated with a six-week course of antibiotics.
- Full text:11.2023my1448.pdf
