Development of lateral flow immunoassay for SARS-CoV-2 antigen detection
- VernacularTitle:侧流免疫层析技术在新型冠状病毒抗原检测中应用的研究
- Author:
Yufei CHENG
1
;
Longhao ZHANG
2
Author Information
1. Core Facilitier, West China Hospital of Sichuan University, Chengdu, 610041, P. R. China
2. Department of Medical Discipline Construction, West China Hospital of Sichuan University, Chengdu, 610041, P. R. China
- Publication Type:Journal Article
- Keywords:
SARS-CoV-2;
point-of-care testing;
lateral flow immunoassay;
review
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2023;30(05):779-783
- CountryChina
- Language:Chinese
-
Abstract:
This article summarizes the development of lateral flow immunoassay for SARS-CoV-2 antigen detection. Lateral flow immunoassay is a rapid, low cost, and ease of use detection tool that has been widely applied in clinical and public health sectors. Since the outbreak of COVID-19, the technique has been adopted for rapid antigen diagnostic test of SARS-CoV-2, including commonly used colloidal gold nanoparticle-based lateral flow immunoassays as well as various fluorescence-based lateral flow immunoassays. With innovations in labelling methods, this detection technique has been in continuous development and is shifting from qualitative toward quantitative as well as gaining sensitivity.
