Advancement in the relationship between gut microbiota and coronary artery disease
- VernacularTitle:肠道菌群与冠心病关系的研究进展
- Author:
Kaiwen LIU
1
;
Kui ZHANG
2
;
Ning ZHOU
2
;
Ran DONG
2
Author Information
1. Capital Medical University, Beijing, 100069, P. R. China
2. Department of Cardiac Surgery, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, 100029, P. R. China
- Publication Type:Journal Article
- Keywords:
Coronary artery disease;
gut microbiota;
atherosclerosis;
trimethylamine N-oxide;
review
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2023;30(05):746-752
- CountryChina
- Language:Chinese
-
Abstract:
Including gut microbiota and oral microbiota, various microorganisms in different human ecosystem constitute the human microbiota, which play an important role in human metabolism, immunity and maintaining microecological homeostasis. Abnormal changes in gut microbiota known as dysbiosis may lead to metabolic abnormalities and inflammatory changes, which are closely related to disease states including hypertension, diabetes, inflammatory bowel disease, and autoimmune diseases. The main cause of coronary artery disease is coronary atherosclerosis, a chronic and progressive inflammatory disease. Many evidences have shown that there is a correlation between gut microbiota and coronary artery disease. Therefore, we aim to review the relationship between gut microbiota and coronary artery disease, and discuss the possible research directions and application prospects.
