Clinical efficacy analysis of different interventional approaches for patent ductus arteriosus in children (≤7 years)

Zeming Zhou; Hongmao Wang; Hong Zheng; Huijun Song; Shiguo LI; Chaowu Yan; Haibo HU; Qiong Liu; Zhongying XU; Liang XU; Jianhua LV; Gejun Zhang; Junyi Wan; Jinglin Jin

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Clinical efficacy analysis of different interventional approaches for patent ductus arteriosus in children (≤7 years)

VernacularTitle:不同介入封堵入路治疗儿童（≤7岁）动脉导管未闭的临床疗效分析
Author: Zeming ZHOU ^{1
,

2} ; Hongmao WANG ^{3
,

4} ; Hong ZHENG ^{1
,

2} ; Huijun SONG ^{1
,

2} ; Shiguo LI ^{1
,

2} ; Chaowu YAN ^{1
,

2} ; Haibo HU ^{1
,

2} ; Qiong LIU ^{1
,

2} ; Zhongying XU ^{1
,

2} ; Liang XU ^{1
,

2} ; Jianhua LV ^{1
,

2} ; Gejun ZHANG ^{1
,

2} ; Junyi WAN ^{1
,

2} ; Jinglin JIN ^{1
,

2}
Author Information

1. Department of Structural Heart Disease, Fuwai Hospital, Chinese Academy of Medical Sciences &
2. Peking Union Medical College, Beijing, 100037, P. R. China
3. Department of Cardiovascular Diseases, Children&rsquo
4. s Hospital Affiliated to Capital Institute of Pediatrics, Beijing, 100020, P. R. China
Publication Type:Journal Article
Keywords: Patent ductus arteriosus; interventional closure; conventional arteriovenous approach; simple venous approach; retrograde femoral artery approach
From: Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2023;30(05):699-703
CountryChina
Language:Chinese
Abstract: Objective To explore the safety and effectiveness of different interventional approaches for the treatment of patent ductus arteriosus (PDA) in children. Methods The children (≤7 years) who underwent interventional treatment for PDA from 2019 to 2020 in our hospital were retrospectively included. The patients were divided into 3 groups according to the procedures: a conventional arteriovenous approach group, a simple venous approach group, and a retrograde femoral artery approach group. The clinical efficacy of the patients was compared. Results A total of 220 patients were included. There were 78 males and 142 females, with an average age of 3.21±1.73 years, weight of 14.99±5.35 kg, and height of 96.19±15.77 cm. The average diameter of the PDA was 3.35±1.34 mm. A total of 85 patients received a conventional arteriovenous approach, 104 patients received a simple venous approach, and 31 patients received a retrograde femoral artery approach. The diameter of PDA in the retrograde femoral artery group was smaller than that in the other two groups (3.44±1.43 mm vs. 1.99±0.55 mm; 3.69±1.17 mm vs. 1.99±0.55 mm, P<0.001); the contrast medium usage [40 (30, 50) mL vs. 20 (20, 30) mL; 35 (25, 50) mL vs. 20 (20, 30) mL, P≤0.001] and operation time [32 (26, 44) min vs. 25 (23, 30) min; 29 (25, 38) min vs. 25 (23, 30) min, P<0.05] in the simple venous approach group were significantly less or shorter than those in the other two groups; the length of hospital stay of the conventional arteriovenous group was longer than that in the other two groups [3 (3, 5) d vs. 4 (3, 6) d; 4 (3, 5) d vs. 4 (3, 6) d, P<0.05]. There was no significant difference in postoperative complications. Conclusion It is safe and effective to close PDA through simple venous approach. The retrograde femoral artery approach has the advantage of simplifying the surgical procedure for PDA with small diameters.