Research progress on non-clinical safety evaluation of SARS-CoV-2 vaccine
10.13200/j.cnki.cjb.003916
- VernacularTitle:SARS-CoV-2疫苗非临床安全性评价的研究进展
- Author:
XIAO Lichun
- Publication Type:Journal Article
- Keywords:
SARS-CoV-2 vaccine;
Animal model;
Pharmacodynamics;
Safety evaluation
- From:
Chinese Journal of Biologicals
2023;36(6):742-750
- CountryChina
- Language:Chinese
-
Abstract:
The Coronavirus Disease 2019(COVID-19) pandemic is having a dramatic impact on human health,lives,and the global economy. The development of a safe and efficacious vaccine is the most effective intervention to protect the population from the disease and limit the spread of the virus. Based on the current guidelines and research progress of severe acute respiratory symptom coronavirus 2(SARS-CoV-2) vaccines in various countries,this review summarized the research progress on non-clinical safety evaluation of SARS-CoV-2 vaccines by referring to the guidelines and relevant literatures over the world,in order to provide a reference for non-clinical research of SARS-CoV-2 vaccines.