Study on the value of pharmaceutical service related to risdiplam based on follow-up data of DTP pharmacy
- VernacularTitle:基于DTP药房回访数据探讨利司扑兰相关药学服务价值
- Author:
Zaihuan SHI
1
;
Fangting WANG
2
;
Zhijun GUO
2
;
Shuohan HUANG
3
;
Linhui ZHU
3
;
Zheyuan WANG
3
;
Qiong DU
3
;
Qing ZHAI
3
Author Information
1. Shangyao Yunjiankang Yiyao Pharmacy （Shanghai） Co.，Ltd.，Shanghai 200032，China
2. Shunde District Heyou Meihe Hospital of Foshan City，Guangdong Foshan 528339，China
3. Dept. of Pharmacy，Fudan University Shanghai Cancer Center，Shanghai 200032，China
- Publication Type:Journal Article
- Keywords:
DTP pharmacy;
pharmaceutical service;
spinal muscular atrophy;
risdiplam;
rare diseases
- From:
China Pharmacy
2023;34(19):2414-2418
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To explore the value of providing pharmaceutical service related to risdiplam in direct-to-patient （DTP） pharmacies. METHODS The follow-up data of spinal muscular atrophy （SMA） patients who purchased and used risdiplam from Shangyao Yunjiankang Yiyao Pharmacy （Shanghai） Co.， Ltd. from May 2021 to January 2023 were collected. The medication information， therapeutic efficacy and the occurrence of adverse events were retrospectively analyzed. RESULTS A total of 42 prescriptions were checked by pharmacists in the DTP pharmacies， and 7 prescriptions were found to be unreasonable （16.7%， 7/42）， which were corrected after the timely intervention. During the follow-up management， pharmacists replied to 4 patients （9.5%， 4/42） regarding medication consultation about medication requirements and adverse events. Two patients with type Ⅰ SMA experienced adverse events： one of them presented with fever and the other presented with skin dryness with darkening. Both of them were grade Ⅰ toxic reactions and generally did not require clinical treatment. Considering that the patient sustained low-grade fever for a long time， the pharmacist suggested symptomatic treatment under the guidance of the doctor. CONCLUSIONS Pharmacists in DTP pharmacies conducting follow-up management of risdiplam use for rare disease SMA patients can help promote rational， standardized medication for patients.
