Progress of Lynch syndrome associated endometrial cancer
10.3760/cma.j.cn115355-20221009-00625
- VernacularTitle:林奇综合征相关子宫内膜癌的诊治进展
- Author:
Yayun MA
1
;
Chen LIANG
;
Sanyuan ZHANG
;
Yan NI
Author Information
1. 山西医科大学研究生院,太原 030001
- Keywords:
Lynch syndrome;
Endometrial neoplasms;
Mismatch repair gene;
Screening;
Treatment outcome
- From:
Cancer Research and Clinic
2023;35(7):549-552
- CountryChina
- Language:Chinese
-
Abstract:
Lynch syndrome (LS) is a common hereditary tumor syndrome. Gynecological malignancy is usually the first tumor of LS in women, and endometrial cancer (EC) is the most closely associated with LS. Most patients with LS are unaware of this risk, and it is possible to cause misdiagnosis. Thus, early diagnosis helps patients to start tumor surveillance timely, as well as a cascade of family surveillance. This paper reviews the progress of LS associated with EC.