Progress of diagnosis and treatment for gastrointestinal neuroendocrine neoplasms
10.3760/cma.j.cn115355-20220304-00127
- VernacularTitle:胃肠-神经内分泌肿瘤的诊治进展
- Author:
Miao HE
1
;
Jing FAN
;
Ziwei WANG
;
Shouru ZHANG
Author Information
1. 重庆大学附属肿瘤医院胃肠肿瘤中心 肿瘤转移与个体化诊治转化研究重庆市重点实验室，重庆 400030
- Keywords:
Carcinoma, neuroendocrine;
Duodenal neoplasms;
Diagnosis;
Antineoplastic protocols
- From:
Cancer Research and Clinic
2023;35(4):309-313
- CountryChina
- Language:Chinese
-
Abstract:
Gastrointestinal neuroendocrine neoplasm (GI-NEN) is an important part of digestive system tumor. With the progress of diagnosis and the further understanding of GI-NEN, the diagnostic rate is increasing. However, GI-NEN is a rare tumor, thus clinicians are not familiar with the diagnosis and treatment. Misdiagnosis and missed diagnosis of GI-NEN often occur, and the treatment regimen is not standardized. In recent years, some progresses of the diagnosis and treatment have been made in GI-NEN, especially in the aspects of pathology, imaging diagnosis, radionuclide therapy, targeted therapy and immunotherapy, which have improved the diagnosis rate and efficacy for GI-NEN. This paper reviews recent literatures of GI-NEN, summarizes its epidemiology, pathological diagnosis, image diagnosis, surgery, targeted therapy, radionuclide therapy, chemotherapy, immunotherapy, and separates GI-NEN into metastatic and non-metastatic groups for detailed review to provide a reference for guiding clinical diagnosis and treatment as well as exploring the new treatment regimens of GI-NEN.
