Progress of the effect of circular RNA on the sensitivity to chemotherapy drugs in colorectal cancer
10.3760/cma.j.cn115355-20221110-00718
- VernacularTitle:环状RNA对结直肠癌化疗药物敏感性影响的研究进展
- Author:
Wenjia YIN
1
;
Quan SHAO
;
Kai SUN
Author Information
1. 山西医科大学研究生院，太原 030001
- Keywords:
Colorectal neoplasms;
Circular RNA;
Chemotherapy drugs;
Sensitivity
- From:
Cancer Research and Clinic
2023;35(4):305-308
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of colorectal cancer involves a variety of molecules and genes, among which circular RNA (circRNA) has received extensive attention in regulating the development and progression of tumors and mediating drug resistance. circNRA has been identified as tumor promoters or tumor suppressors that influence the sensitivity to chemotherapy drugs and mediate the onset and metastasis of colorectal cancer. The influence of circRNA on the drug resistance sensitivity of conventional chemotherapy has become a new direction for the research of anti-tumor chemotherapy drugs. This paper discusses the biological characteristics of circRNA and introduces the relationship between circRNA and the sensitivity to chemotherapy drugs in colorectal cancer.
